Midterm Exam: NR507/ NR 507 (2023/ 2024
New Update) Advanced Pathophysiology
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QUESTION
Anemia's pre-quiz Qs
QUESTION
Which of the following indices measures the average size of red blood cells?
a. Hemoglobin (Hb).
b. Reticulocyte count.
c. Mean Corpuscular Volume (MCV).
d. Mean Corpuscular Hemoglobin Concentration (MCHC).
Answer:
c. Mean Corpuscular
Volume (MCV).
QUESTION
Which of the following microcytic anemias is characterized by hyper- chromic RBCs?
a. B12 deficiency. b. Iron deficiency.
c. Folate deficiency.
d. Hereditary spherocytosis.
Answer:
d. Hereditary spherocytosis.
QUESTION
Which of the following is not a clinical characteristic of anemia?
a. Fatigue
b. Bradycardia c. Dyspnea
d. Pallor
Answer:
b. Bradycardia
QUESTION
Anemia can be caused from which of the following? (Select all that apply.) Increased red blood
cell destruction.
Impaired red blood cell production. Excessive blood loss.
Answer:
all of the three
QUESTION
What is Anemia?
Answer:
Anemia is a hematological disorder characterized by a reduction in the total number of
circulating red blood cells (RBCs) and/or a decrease in hemoglobin (Hb) amount or function
QUESTION
Anemia can be caused by
Answer:
1) impaired RBC production,
2) excessive blood loss,
3) increased RBC destruction OR any combination of the three.
QUESTION
In order to recognize and differentiate the type of anemia that is present, it is important to
understand the components that relate to red blood cells and their production. List and define
them
Answer:
Red blood cells (RBC):
The number of erythrocytes in 1 cubic mm of whole blood. Normal for men is 4.7 -6.1 mcL.
Normal in women is 4.5-5.2 mcL. Hemoglobin (Hb):
The oxygen-carrying pigment of red cells. Normal for men is 13.5-17.5 g/dL.
Normal for women is 12.0-15.5 g/dL.
QUESTION
In order to recognize and differentiate the type of anemia that is present, it is important to
understand the components that relate to red blood cells and their production. List and define
them
Answer:
Reticulocyte:
Immature RBCs. Used to assess bone marrow function. Normal in adults is approximately 3%.
Mean Cell Volume (MCV):
This measures the average size of the RBC. Normal is 80-100 fL.
Mean Corpuscular Hemoglobin (MCH): Average weight of hemoglobin per red cell. Normal is
27-33 pg.
Mean Corpuscular Hemoglobin Concentration (MCHC):
Average concentration of hemoglobin per erythrocyte. Normal is 32-36%.
QUESTION
Anemia Classification
Anemias can be classified into 3 categories based on the average size of the RBCs (MCV): list
them
Answer:
Microcytic anemia (MCV<80 fL) describes RBCs that are small.
Macrocytic anemia (MCV>100 fL) describes RBCs that are large. Normocytic anemia (MCV
80-99 fL) describes RBCs that are normal in size.
QUESTION
Anemias can also be classified according to the color of the RBCs: List them
Answer:
Hypochromic anemia describes RBCs with less hemoglobin than normal. As a result, the RBCs
appear pale in color (MCHC is low).
Hyperchromic anemia describes RBCs with more hemoglobin than n result, the RBCs appear a
dark hue or red than normal cells (MCHC i Normochromic anemia describes RBCs that have a
normal amount of hemoglobin. As a result, the RBCs appear neither pale nor dark (MCHC is
normal).
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