bacteriostatic - CORRECT ANSWER drugs that do not kill the bacteria, but slows their growth
culture and sensitivity - CORRECT ANSWER take a blood culture
... [Show More] so we can determine where
the bacteria is growing; sensitivity report determines the best treatment
antibiotic combos - CORRECT ANSWER Additive
potentiative
antagonisitic
empiric therapy - CORRECT ANSWER treatment of an infection before specific culture
information has been obtained
definitive therapy - CORRECT ANSWER antibiotic therapy tailored to treat organisms
identified with cultures
prophylactic therapy - CORRECT ANSWER treatment with antibiotics to prevent an infection,
as in intraabdominal surgery or after trauma
MOA of sulfonamides - CORRECT ANSWER Bacteriostatic
inhibit bacterial growth
prevent bacterial synthesis of folic acid
uses of sulfonamides - CORRECT ANSWER Gramp positive and negative, broad spectrum
respiratory tract infections
infections of the small bowel
UTIs: enterobacter, ecoli, klebsiella, proteus vulgaris, staphylococcus aureus
contraindications of sulfonamides - CORRECT ANSWER drug allergy
pregnant women
infants younger than 2 months
potassium
oral contraceptives (ineffective)
Adverse effects of sulfonamides - CORRECT ANSWER mild to moderate rash
photosensitivity
GI distress
stomatitis
crystalluria
fatigue
depression
headache
dizziness
blood dyscrasias
Steven Johnsons syndrome
renal failure
hyperkalemia
prototype for sulfonamides, and administration - CORRECT ANSWER sulfamethoxazole
combined with trimethropim
Administered IV, PO, Topical
patient education/ nursing interventions for sulfonamides - CORRECT ANSWER Pt. Education:
take with a full glass of water
increase fluid intake
report sore throat, bruising, bleeding
avoid direct sunlight
Nursing interventions:
push fluids
Monitor CBC
signs of bleeding (liver damage)
check for superinfection
beta lactam penicilins MOA - CORRECT ANSWER safest class
bacteriocidal
inhibition of bacterial cell wall synthesis
uses of penicillins - CORRECT ANSWER strep
staph
pneumonia
meningitis
skin, bone, and joint infections
stomach infections
blood and valve infections
gas gangrene
tetanus
anthrax
sickle cell anemia in infants
broad spectrum penicillin - CORRECT ANSWER bacteriocidal
ecoli
salmonella
influenza
adverse effects of penicillin - CORRECT ANSWER allergy most common
rash
pruritus
fever
anaphylaxis
lowered WBC, RBC, platelet count
GI upset
patient education for penicillins - CORRECT ANSWER side effects
bleeding
increase fluid intake
take with food
drugs for penicillin - CORRECT ANSWER broad spectrum:
amoxicillin
combination:
piperacillin plus tazobactam (zosyn)
give 3 times a day infused over 4 hours or every 6 hours infused over 1 hour
cephalosporins MOA - CORRECT ANSWER largest class
interfere with bacterial cell wall synthesis, bind to the same penicillin binding proteins
uses of cephalosporins - CORRECT ANSWER treatment of gram positive and negative
anaerobic bacteria
mostly gram negative
patients who cannot tolerate the less expensive penicillins
respiratory infections
urinary infections
skin infections
bone and joint infections
genital infections
contraindications of cephalosporins - CORRECT ANSWER may cause cross allergy potential
with penicillin
adverse effects of cephalosporins - CORRECT ANSWER weakness
pruritus
GI distress
high doses can cause
bleeding
seizures
nephrotoxicity
patient education of cephalosporins - CORRECT ANSWER side effects
administration
monitor kidney function with 1st generation
drugs for cephalosporins - CORRECT ANSWER first generation
Cefazolin (ancef)
not effective for beta lactase
gram positive bacteria
may cause kidney toxicity
macrolides MOA - CORRECT ANSWER broad spectrum
inhibit protein synthesis
binds reversibly to 50S ribosomal subunits of microbes [Show Less]