Chemical name - CORRECT ANSWER Describes the drug's chemical composition and
molecular structure
Ex: (+/-)-2-(p-isobutylephenyl) propionic
... [Show More] acid
Generic name - CORRECT ANSWER Nonproprietary name
-Given by the United States Adopted Names Council
-Used in most official drug compendiums to list drugs
Ex: Ibuprofen
Trade name - CORRECT ANSWER Proprietary name
-The drug has a registered trademark; use of the name is restricted by the drug's patent owner
(usually the manufacturer)
Ex: Motrin, others
____________ determines the rate of drug dissolution - CORRECT ANSWER Dosage form
Drug dissolution - CORRECT ANSWER dissolving of solid dosage forms and their absorption
from the GI tract
Fastest drug absorption - CORRECT ANSWER Oral disintegration, buccal tablets, oral soluable
wafers
Slowest drug absorption - CORRECT ANSWER Enteric-coated tablets
Drug absorption from fastest to slowest - CORRECT ANSWER -Oral disintegration, buccal
tablets, oral soluable wafers
-Liquids, elixirs, and syrups
-Suspension solutions
-Powders
-Capsules
-Tablets
-Coated tablets
-Enteric-coated tablets
Absorption - CORRECT ANSWER Movement of a drug from its site of administration into the
blood stream for distribution to the tissues
Bioavailablitiy - CORRECT ANSWER Extent of drug absorption
Medication routes - CORRECT ANSWER -Enteral
-Parenteral
-Topical
Enteral - CORRECT ANSWER (GI tract)
-orally vs sublingual and buccal routes, G tube
-First pass effect, variable absorption
Patenteral - CORRECT ANSWER -Intravenous (IV)
-Intramuscular (IM)
Intravenous (IV) - CORRECT ANSWER Rapid onset
Avoid first pass effect
IV: Nursing considerations - CORRECT ANSWER Monitor drug
Check for compatibilities
Monitor IV site
Intramuscular (IM) - CORRECT ANSWER Subcutaneously
Topical - CORRECT ANSWER Avoid first-pass effect, except rectal administration
-Transdermal
-Topical
Transdermal - CORRECT ANSWER Deliver constant amount
Slower onset, prolong duration
Patent life - CORRECT ANSWER Length of time from patent approval until patent expiration
-Normally 17 years in newly discovered drug molecule
Biosimilar - CORRECT ANSWER Copy version of an already authorized biological product
-New category of the generic drug market
Therapeutic equivalence - CORRECT ANSWER One drug in a class of several drugs is chosen
as the preferred agent, even though the drugs do not have the same active ingredients
-In place due to high cost of drugs
-Both drugs have same therapeutic effect on the body
Drug classification - CORRECT ANSWER Drugs are grouped together based on their similar
properties
-Can be classified by structure or therapeutic use
Three basic areas of pharmacology that describe the relationship between the dose of a drug and
the activity of that drug in treating the disorder - CORRECT ANSWER Pharmaceutics
Pharmacokinetics
Pharmacodynamics
Pharmaceutics - CORRECT ANSWER The study of how various drug forms influence the way
in which the drug affects the body
-Different drug dosage forms have different pharmaceutical properties
Pharmacokinetics - CORRECT ANSWER The study of what the body does to the drug
-Involves absorption, distribution, metabolism, and excretion
Pharmacodynamics - CORRECT ANSWER The study of what the drug does to the body
-Involves drug-receptor relationships
Pharmacotherapeutics - CORRECT ANSWER (Therapeutics)
Focuses on clinical use of drugs to prevent and treat diseases
-Defines the principles of drug actions
Phases of drug activity - CORRECT ANSWER Administration
1. Pharmaceutical phase: Disintegration of dosage form; dissolution of drug in body
Drug available for absorption
2. Pharmacokinetic phase: Absorption, distribution, metabolism, excretion
Drug available for action
3. Pharmacodynamic phase: Drug-receptor interaction
Effect
Off-label prescribing - CORRECT ANSWER Use of drugs for non-FDA-approved indications
Toxicology - CORRECT ANSWER Study of adverse effects of drugs and other chemicals on
living systems
Toxic effects - CORRECT ANSWER Often an extension of a drug's therapeutic action.
Pharmacognosy - CORRECT ANSWER The study of natural drug sources
(plants, animals, minerals) [Show Less]