inflammatory mediators - end results of inflammation, help us to heal, but cause pain and swelling along the way
--pain, heat, redness,
... [Show More] swelling
corticosteroids - group of steroidal hormones.
cortisol - prototypical, naturally occuring (endogenous) corticosteroid
-produced in the outer part (cortex) of the adrenal glands that sit on top of the kidneys
-modulate glucose levels and body responses to stress
-temper the immune function, and decrease inflammatory response
eicosanoids - local hormones that are derived from lipid molecules on the cell membrane of virtually all body cells
--involved in regulating a number of different physiologic processes from birth and BP, to inflammation and pain
corticosteroids are better antiinflammatories than COX-inhibitors (like aspirin) because they inhibit all aspects of the __________ _____ _________ - arachidonic acid cascade
because they work upstream of arachidonic acid, corticosteroids also inhibit..... - leukotrienes produced from the lipoxygenase enzyme
over a long period of use, patient taking corticosteroids actually develop a characteristic body habitus and the person is said to be _______ - cushinoid
corticosteroids have systemic major side effects, so we try to use them ______ __ _______ - regionally or locally
cortisone - a synthetic derivative of the natural corticosteroid hormone cortisol
Cortenema - hydrocortisone is formulated in prescription strength as an enema
--for use in cases of Crohn's disease/ulcerative colitis
--corticosteroid
prednisone - one of the most popular, potent corticosteroids
--usually administered orally
--corticosteroid
hydrocortisone - can be found in OTC creams
--you might find them to be too weak, and may need prescription strength steroids
--corticosteroid
methylprednisolone - Solu-Medrol
for IV administartion in emergency cases, such as treatment of anaphylaxis
--corticosteroid
triamcinolone - Kenalog
popular prescription strength creams and ointments
--corticosteroid
betamethasone - popular prescription strength creams and ointments
--corticosteroid
estradiol - Ez
predominant estrogen in nonpregnant women, produced primarily by developing ovarian follicles
testosterone - male sex steroid
most important male androgen hormone
dihydrotestosterone - male sex steroid
most important male androgen hormone
(DHT)
Dianabol - --methandrostenolone
synthetic drug of abuse
first anabolic steroid in the US, developed for olympic athletes
Recombinant Human Growth Hormone - r-HGH
produced as the drug Genotropin
--nonsteroid protein based hormone
--often abused, leads to acromegaly
anabolic steroids - anabolic-androgen steroids(AAS)
-"roids" or "arnolds"
-mimic the effects of testosterone and DHT
4% topical cocaine - decongestant
--if not for the controlled status of this drug it would be our best decongestant with the added benefit of a great local anesthesia
--still used in some ENT practices
phenylephrine - Neo-Synephrine
decongestant
"remember the ANS"
topical preparation
Contact-widely available, but only marginally effective at relieving a stuffy nose
oxymetazoline - Afrin Nasal Spray
decongestant
topical preparation
pseudoephedrine - Pfizer's original formulation
Sudafed
kept behind the counter for pharmacist supervision [Show Less]