Acebutolol - ✔✔ HTN, ventricular arrhythmias
*B1 blocker with mild intrinsic sympathomimetic activity*
AE: heart failure, hypoglycemia
... [Show More] unawareness, bradycardia, hypotension, potential bronchospasm in asthmatics, impotence
Acetaminophen - ✔✔ Pain, fever, headache
*Nonopiate, nonsalicylate, non-NSAID analgesic/antipyretic; Reversibly inhibits COX in CNS*
AE: hepatic failure in overdose - treat with N-acetylcysteine
Acetazolamide - ✔✔ Glaucoma, high altitude sickness, edema if accompanied by metabolic alkalosis, urinary alkalization
*Carbonic anhydrase inhibitor, CA catalyzes reversible reaction of combining CO2 and H2O to form carbonic acid*
AE: hypochloremic metabolic acidosis, renal stones, hypokalemia, paresthesias, hepatic encephalopathy in cirrhotic patients
Acyclovir - ✔✔ Herpes simplex
*Inhibits viral DNA polymerase*
AE: N/V, neurotoxicity, nephrotoxicity
Albuterol - ✔✔ Asthma
*B2 agonist* (alBuTerol = Beta-Two)
AE: tremor, tachycardia, CNS stimulation, hypertension
Alendronate - ✔✔ Osteoporosis
*Bisphosphonate*
AE: esophageal ulcers, esophagitis, abdominal pain, gastric reflux, dysphagia, osteonecrosis of the jaw
Allopurinol - ✔✔ Gout
*Xanthine oxidase inhibitor (irreversible suicide inhibitor)*
AE: rash that can progress to Stevens-Johnson, generalized vasculitis, irreversible hepatotoxicity
Alprazolam - ✔✔ Anxiety
*BZD, increases FREQUENCY of GABA-A receptor opening*
AE: drowsiness, anterograde amnesia, decreased motor skills, dependence, respiratory depression with high doses - reversed with Flumazenil
Alteplase - ✔✔ Acute MI, stroke, pulmonary embolism
*Tissue-plasminogen activator*
AE: bleeding
alTePlAse = TPA
Amiloride - ✔✔ HTN, CHF
*Potassium-spairing diuretic, blocks Na channels in cortical collecting tubules*
AE: hyperkalemia
Amiodarone - ✔✔ Cardiac arrhythmias
*Antiarrhythmic class III, K channel blocker*
AE: *pulmonary fibrosis*, deposits in skin, photosensitivity, thyroid dysfunction, can worsen arrhythmias
Amitriptyline - ✔✔ Depression, anxiety
*TCA, blocks NET and SERT*
AE: *strong anticholinergic side effects*, cardiac arrhythmias with overdose
Can be used 1st line for *migraine prophylaxis*
Amlodipine - ✔✔ HTN, coronary artery disease
*Calcium channel blocker*
AE: dizziness, edema, somnolence, palpitations
Amoxicillin - ✔✔ Respiratory tract infections, otic infections, UTIs
*Beta-lactam antibiotic (penicillin), binds PBP to block transpeptidase cross-linking of peptidoglycan*
AE: diarrhea, maculopapular rash (w/ mononucleosis), pseudomembranous colitis, anaphylactic reactions
Amoxicillin/Potassium Clavulanate - ✔✔ Respiratory tract infections, otic infections, UTIs
*Beta-lactam antibiotic (penicillin)/Beta-lactamase inhibitor*
AE: diarrhea, maculopapular rash (w/ mononucleosis), pseudomembranous colitis, anaphylactic reactions
Amphetamine - ✔✔ ADHD
*Stimulant, blocks VMAT* (vesicular monoamine transporter)
-Increase catecholamines (N.E., dopamine) in synaptic cleft
AE: CNS stimulation, tachycardia, cardiac arrhythmias, dependence
Amphotericin B - ✔✔ Systemic mycoses
*Antifungal, binds ergosterol*
AE: chills and fevers, hypotension, *nephrotoxicity (dose-limiting)*
Ampicillin - ✔✔ UTIs, URIs
*Beta-lactam antibiotic (penicillin), binds PBP to block transpeptidase cross-linking of peptidoglycan*
AE: diarrhea, maculopapular rash (w/ mononucleosis), pseudomembranous colitis, anaphylactic reactions
Anastrozole - ✔✔ Estrogen-dependent breast cancer in postmenopausal women
*Aromatase inhibitor (decreases estrogen synthesis)*
AE: hot flushes, fatigue
Aripiprazole - ✔✔ Schizophrenia, bipolar disorder
*Atypical antipsychotic, D2 antagonist and partial agonist, also D4 antagonist and 5HT1A partial agonist*
AE: fewer EPS than typical antipsychotics, less weight gain and sedation than other atypical antipsychotics, few anticholinergic effects [Show Less]