MOOD D/O:
MDD CRITERIA A
A. Five (or more) of the following symptoms have been present during the same 2-week
period and represent a change from
... [Show More] previous functioning; at least one of the symptoms
is either (1) depressed mood or (2) loss of interest or pleasure.
Note: Do not include symptoms that are clearly attributable to another medical condition.
1. Depressed mood daily
2. Loss of pleasure of joy in activities/inerests
3. Significant weight loss/gain
4. insomnia/hypersomnia
5. fatigue or loss of energy daily
6. psychomotor retardationagitation
7. feelings of worthlessness or guilt
8. diminished ability to think/concentrate, indecisiveness
9. recurrent thoughts of death, SI, or SI attempt
MOOD D/O: MDD CRITERIA B-E
B. The symptoms cause clinically significant distress or impairment in social, occupational,
or other important areas of functioning.
C. The episode is not attributable to the physiological effects of a substance or to another
medical condition.
D. The occurrence of the major depressive episode is not better explained by schizoaffective
disorder, schizophrenia, schizophreniform disorder, delusional disorder, or
other specified and unspecified schizophrenia spectrum and other psychotic disorders.
E. There has never been a manic episode or a hypomanic episode.
Note: This exclusion does not apply if all of the manic-like or hypomanic-like episodes
are substance-induced or are attributable to the physiological effects of another medical
condition.
MOOD D/O: MDD PREVALENCE
Twelve-month prevalence of major depressive disorder in the United States is approximately
7%, with marked differences by age group such that the prevalence in 18- to 29-year-old individuals
is threefold higher than the prevalence in individuals age 60 years or older. Females experience
1.5- to 3-fold higher rates than males beginning in early adolescence.
MOOD D/O: MDD DEVELOPMENT AND COURSE
-Recovery typically begins within 3 months of onset for two in five individuals with major
depression and within 1 year for four in five individuals.
-The risk is higher in individuals whose preceding episode was severe,
in younger individuals, and in individuals who have already experienced multiple episodes.
-The persistence of even mild depressive symptoms during remission is a powerful
predictor of recurrence.
MOOD D/O: MDD RISK FACTORS
-Neuroticism (negative affectivity) is a well-established risk factor for the
onset of major depressive disorder
-Adverse childhood experiences, particularly when there are multiple experiences of diverse types, constitute a set of potent risk factors for major depressive disorder.
-Stressful life events are well recognized as precipitants of major depressive episodes,but the presence or absence of adverse life events near the onset of episodes does not appear to provide a useful guide to prognosis or treatment selection.
-First-degree family members of individuals with major depressive disorder have a risk for major depressive disorder two- to fourfold higher than that of the general population.
-Relative risks appear to be higher for early-onset and recurrent forms. Heritability is approximately 40%, and the personality trait neuroticism accounts
for a substantial portion of this genetic liability.
MOOD D/O: PDD (DYSTHYMIA) DSM5 CRITERIA
Depressed mood for most of the day, for more days than not, as indicated by either
subjective account or observation by others, for at least 2 years.
Note: In children and adolescents, mood can be irritable and duration must be at least
1 year.
B. Presence, while depressed, of two (or more) of the following:
1. Poor appetite or overeating.
2. Insomnia or hypersomnia.
3. Low energy or fatigue.
4. Low self-esteem.
5. Poor concentration or difficulty making decisions.
6. Feelings of hopelessness.
C. During the 2-year period (1 year for children or adolescents) of the disturbance, the individual has never been without the symptoms in Criteria A and B for more than 2 months at a time.
D. Criteria for a major depressive disorder may be continuously present for 2 years.
E. There has never been a manic episode or a hypomanic episode, and criteria have never been met for cyclothymic disorder.
F. The disturbance is not better explained by a persistent schizoaffective disorder, schizophrenia, delusional disorder, or other specified or unspecified schizophrenia
spectrum and other psychotic disorder.
G. The symptoms are not attributable to the physiological effects of a substance (e.g., a drug of abuse, a medication) or another medical condition (e.g. hypothyroidism).
H. The symptoms cause clinically significant distress or impairment in social, occupational,
or other important areas of functioning.
Note: Because the criteria for a major depressive episode include four symptoms that are absent from the symptom list for persistent depressive disorder (dysthymia), a very limited number of individuals will have depressive symptoms that have persisted longer than 2 years but will not meet criteria for persistent depressive disorder. If full criteria for a major depressive episode have been met at some point during the current episode of illness, they should be given a diagnosis of major depressive disorder. Otherwise, a diagnosis of other specified depressive disorder or unspecified depressive disorder is warranted.
MOOD D/O: DYSTHYMIA PREVALENCE
The 12-month prevalence in the United States is approximately
0.5% for persistent depressive disorder and 1.5% for chronic major depressive disorder.
MOOD D/O: DYSTHYMIA DEVELOPMENT COURSE
Persistent depressive disorder often has an early and insidious onset (i.e., in childhood,
adolescence, or early adult life) and, by definition, a chronic course. Among individuals
with both persistent depressive disorder and borderline personality disorder, the covariance
of the corresponding features over time suggests the operation of a common mechanism.
Early onset (i.e., before age 21 years) is associated with a higher likelihood of
comorbid personality disorders and substance use disorders.
MOOD D/O: DYSTHYMIA RISK FACTORS
-Factors predictive of poorer long-term outcome include higher levels of neuroticism (negative affectivity), greater symptom severity, poorer global functioning, and presence of anxiety disorders or conduct disorder.
-It is thus likely that individuals with persistent depressive disorder will have a higher proportion of first-degree relatives with persistent depressive
disorder than do individuals with major depressive disorder, and more depressive disorders
in general.
-A number of brain regions (e.g., prefrontal cortex, anterior cingulate, amygdala, hippocampus)
have been implicated in persistent depressive disorder. Possible polysomnographic
abnormalities exist as well.
CN I
olfactory-smell
sensory
CN II
Optic - vision
sensory
CN III
Oculomotor Nerve-
Motor
Controls eye movement, pupil constriction, & eyelid movement
CN IV
trochlear nerve-down and inward eye movement
motor
CN V
trigeminal nerve-muscles of mastication; sensation of face, scalp cornea, mucus membranes and nose
-assess the face for strength and sensation
sensory and motor
CN VI
abducens nerve-lateral eye movement
motor
CN VII
facial nerve-move face, close mouth and eyes, taste, saliva and tear secretion
-assess mouth for taste
-assess the face for symmetrical movement
sensory and motor
CN VIII
acoustic
sensory: hearing and equilibrium
CN IX
glossopharyngeal-PHONATION, GAG REFLEX CAROTID REFLEX SWALLOWING TASTE
-assess mouth for taste
-assess mouth for movement of soft palate and the gag reflex
-assess swallowing and speech
sensory and motor
CN X
vagus-TALKING, SWALLOWING, GENERAL SENSATION FROM THE CAROTID BODY, CAROTID REFLEX
-assess mouth for movement of soft palate and the gag reflex
-assess swallowing and speech
sensory and motor
CN XI
spinal accessory-movement of trapezius and sternomastoid muscles
-assess the shoulders for strength
motor
CN XII
hypoglossal-tongue movement
motor [Show Less]