analgesic and anti-inflammatory drug? NSAID has more enterogenic effect? ( Piroxicam )
2. MOA of anti-inflammatory ? ( Decrease prostaglandin )
3. Most
... [Show More] likely drug causes Peptic ulcer? Piroxicam Or Ketorolac Or Indomethacin
4. Man take overdose from drug then take the antidote but still no effect, why? ( antidote dose was small )
5. Biological substance can be stored at … C ? ( 2 – 8 C )
6. What pharmacist should do when wrong medication prescribed from Dr? ( Inform prescriber doctor )
7. What should do with elderly man with hypertension? ( start with small initial dose then increase )
8. What should do with girl has seizure and tremor رعشه when use Oxcarbazepine "anti-convulsant" ? ( shift to Topiramate ) "Topamax"
9. TTT of trigeminal neuralgia ? ( Carbamazepine ) "Tegretol"
10. Child taking Oxcarbazepine suffers from rash and redness, ? shirf to Topiramate Or Ethosuximide N.B ; this shifting is due to the child because this S.E is normal side effect ,, in case of adult ; keep using Oxcarbazepine
11. Medication is used to treat absence seizures ? ( Ethosuximide )
12. Pt suffered before from migraine attack with aura, he needs drug as prophylaxis? ( Topiramate 25 mg twice )
13. Middle age man has HbA1c=9 and he takes Glipizide + Lisinopril + Pioglitazone علاج سكر Dr add ? ( insulin )
14. Example of drug - disease interaction? ( Pioglitazone & heart failure ) ( Celecoxib & Cardiac toxicity )
15. Woman wants to be pregnant, she takes metformin and pioglitazone, she has history of hypoglycemic and prefers oral therapy, best TTT? ( Stop pioglitazone and titrate metformin ) N.B ; side effect of pioglitazone is Hypoglycemic
16. Normal range of HbA1c is ; non-diabetic 4 – 5.6
17. Bioavailability of Diclofenac injection in muscle ; 100%
18. Bioavailability refers to extent and rate at which the active moiety enters…..? ( systemic circulation ) "site of action"
19. Heparin & Warfarin are contra-indicated with? ( Aspirin & Diclofenac & ibuprofen )
20. Heparin or Warfarin if I added to Aspirin will lead to? ( Bleeding )
21. Interaction between warfarin and ibuprofen cause risk of bleeding, why? ( warfarin will be replaced by ibuprofen )
22. Warfarin oral anti-coagulant is determined or calculated by? ( INR international normalized ratio )
23. Heparin injection anti-coagulant is determined by? ( APTT activated partial thromboplastin time )
24. Heparin and warfarin were prescribed for patient, how long he will take heparin and how much INR ? ( take heparin for 2 days with warfarin then stop heparin , warfarin biological T1/2 is 48 hours
25. Best counseling point for patients taking warfarin? ( Vit K consistent )
26. Anti-dote of warfarin? Vitamin K other name Phytomenadion , phylloquinone K1 , menaquinone K2 , menadione K3
27. Anti-dote of Heparin? Protamine sulfate
28. Anti-dote of Paracetamol? N-Acetyl Cysteine Anti-dote of iron? Deferoxamine
29. Drug acts on non-receptor mechanism? Drug is used to remove excess iron by binding to free iron? Deferoxamine
30. Which decreases warfarin actions? Multivitamins
31. Which drug cause nasal bone hypoplasia? Warfarin
32. Drug that increases action of Warfarin? None of the above
33. Why should warfarin be stopped if woman want to be pregnant? Cranial facial abnormality [Show Less]