What is the appropriate anticoagulant if CHAD score is 5 ?
Answer
Aspirin, clopidogrel, dabigatran 2 or more(OAC)
2
In patient with septic shock what
... [Show More] is the most important step?
Answer
A- Take cultures
B-Administer fluid
C-Give empirical antibiotics
3
In child with ADHD what is the appropriate choice?
Answer
A- guanfacine once daily
B- Methylphenidate once daily
C- Methylphenidate 6-time daily
D- Methylphenidate prn
For preschool children (age 4 through 5 years) who meet the diagnostic criteria for ADHD, medication as the initial therapy When we recommend behavior therapy rather than rather than methylphenidate medication is necessary for preschool children, we suggeststimulants-amphetamines or non
aged children (≥6 years) and adolescents with ADHD who meet specific -For most schoolcriteria , we suggest treatment with medication rather than behavior therapy alone or no intervention
4
In Irritable bowel syndrome what is the most causative factor?
Answer
Psychosocial stressor
Genetic predisposition
Experts think these problems may play a role in causing IBS. These problems include Stressful or difficult early life events, such as physical or sexual abuse Certain mental disorders, such as depression , anxiety , and somatic symptom disorder Bacterial infections in your digestive tract Small intestinal bacterial overgrowth, an increase in the number or a change in the type of bacteria in your small intestine Food intolerances or sensitivities, in which certain foods cause digestive symptoms may make some people more likely to develop IBS. genes Research suggests that
5 What is the most common side effect of bisphosphonate
Answer
Oral bisphosphonates may cause local irritation of the upper gastrointestinal (GI) mucosa, resulting in reflux, esophagitis, and/or esophageal ulcers.
Intravenous (IV) bisphosphonates are often associated with an acute-phase reaction within 24 to 72 hours of the infusion, characterized by low-grade fever, myalgias, and arthralgias.
Both oral and IV bisphosphonates can cause transient hypocalcemia, but more frequently after IV than oral administration.
Rarely, patients have experienced severe musculoskeletal pain (bone, joint, and/or muscle pain) within days, months, or years after starting a bisphosphonate, and symptoms do not always resolve completely with discontinuation of therapy
6
Which bisphosphonate is associated with gastric ulcer?
Answer Alendronate, Risedronate)Oral bisphosphonates (
7
Which treatment of osteoporosis could be given monthly?
Answer DOSING FREQUENCY FORMULATION BISPHOSPHONATE
Daily or weekly Oral tablet Alendronate
Daily or monthly Every 3 months
Oral tablet Intravenous Ibandronate
Daily or weekly Oral tablet Risedronate
Twice monthly or monthly
Oral delayed-release tablet
Yearly Intravenous Zoledronic acid
DOSING INSTRUCTIONS FOR ORAL BISPHOSPHONATES
• Take with 6 to 8 ounces of plain water only
[Note: Take risedronate delayed-release tablet with at least 4 ounces of plain water]
• Take at least 30 minutes (60 minutes for ibandronate) BEFORE other food, drink, or medications
[Note: Take risedronate delayed-release tablet immediately AFTER breakfast]
•Remain upright and do not lie down or recline for at least 30 minutes (60 minutes for ibandronate) after taking
8
What is the dose of ferrous sulfate that treat anemia?
Answer
100 TID
500 BID tablet contains 65 mg of elemental iron per tablet; three tablets per ferrous sulfate A 325 mgmg of elemental ironday will provide 195
9
Treatment of hypertension in black patient?
Answer
A thiazide-like diuretic or long-acting dihydropyridine calcium channel blocker should be used as initial monotherapy in black patients
10
Which hormone is associated with fetal productive abnormalities?
Answer
Androgen, Estrogen, progesterone
11
8-what is equivalent to omeprazole 20 mg?
Answer
A-esomeprazole 40 mg
B-Pantoprazole 40 mg
C-Ranitidine 300 mg daily
12
How to start anti- hypertension in elderly?
Answer
A-Start low dose and increase gradually
B-Start normal dose and decrease gradually
C-Not different from adult dose
13
Phase 1 of drug development
Answer
A-pharmacokinetics study in human
B-Safety and efficacy in human
In phase1 Goal is to gather information on the pharmacokinetic and pharmacodynamics properties
14
Progestin can be used in breast feeding women
Answer The weight of an adequate body of evidence and/or expert consensus suggests this drug (Micromedex) poses minimal risk to the infant when used during breastfeeding Progesterone is present in breast milk. The manufacturer recommends that caution be used if progesterone is administered to a breastfeeding female.(uptodate)
15
Side effect of albuterol
Answer
Common:
Tachycardia, Nausea , Pharyngitis , Viral gastroenteritis , Vomiting, Backache
Feeling nervous, Headache, Sinus headache, Tremor, Urinary tract infectious disease
Bronchitis, Cough, Nasopharyngitis, Pain in throat, Rhinitis , Sinusitis, Upper respiratory infection, Pain.
16
CYP2D6 with codeine when the effect is reduce?
Answer
(Poor metabolizer, rapid metabolizer)
17
Septic shock 1st line?
Answer
Norepinephrine IV infusion
18
Status epilepticus treatment
Answer line treatment for convulsive status epilepticus because they -Benzodiazepines are the firstcontrol seizures rapidly ]; midazolam is preferred for 6preferred in adults [For IV therapy, lorazepam is rectal intramuscular (IM), intranasal or buccal therapy; and diazepam is preferred foradministration. line agent-Use of lorazepam as a first – Lorazepam
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