NSG 5003 WEEK 1 KNOWLEDGE CHECK QUIZ 1 & 2
NSG 5003 WEEK 1 KNOWLEDGE CHECK QUIZ 1 & 2
1) An organelle that is responsible for metabolism of
... [Show More] cellular energy is referred to which of the following cell structures?
2) Which of the following options is a chemical agent that causes cell injury?
3) Breast changes of a girl in puberty or of a pregnant woman describe which type of cellular adaptation?
4) An active process of programmed cellular self-destruction (cell death) describes which of the following cell functions?
5) When extracellular fluid is hypotonic what is the resulting impact on the cell?
NSG 5003 WEEK 3 KNOWLEDGE CHECK QUIZ 2
Question 1
Oncogenes are genes that are capable of:
a)
Undergoing mutation that directs the synthesis of proteins to accelerate the rate of tissue proliferation
b)
Directing synthesis of proteins to regulate growth and to provide necessary replacement of tissue
c)
Encoding proteins that negatively regulate the synthesis of proteins to slow or halt the replacement of tissue
d)
Undergoing mutation that directs malignant tissue toward blood vessels and lymph nodes for metastasis
Question 2 (0.5 points) Question 2 Saved
Burkitt lymphomas designate a chromosome that has a piece of chromosome 8 fused to a piece of chromosome 14. This is an example of which mutation of normal genes to oncogenes?
Question 2 options:
a)
Point mutation
b)
Chromosome translocation
c)
Gene amplification
d)
Chromosome fusion
Question 3 (0.5 points) Question 3 Saved
In childhood neuroblastoma, the N-myc oncogene undergoes which type of mutation of normal genes to oncogenes?
Question 3 options:
a)
Point mutation
b)
Chromosome fusion
c)
Gene amplification
d)
Chromosome translocation
Question 4 (0.5 points) Question 4 Saved
Which aberrant change causes the abnormal growth in a retinoblastoma?
Question 4 options:
a)
Proto-oncogenes are changed to oncogenes.
b)
The tumor suppressor gene is turned off.
c)
Genetic amplification causes the abnormal growth.
d)
Chromosomes 9 and 21 are fused.
Question 5 (0.5 points) Question 5 Saved
Two hits are required to inactivate tumor suppressor genes because:
Question 5 options:
a)
Each allele must be altered, and each person has two copies, or alleles, of each gene, one from each parent.
b)
The first hit stops tissue growth, and the second hit is needed to cause abnormal tissue growth.
c)
Tumor suppressor genes are larger than proto-oncogenes, requiring two hits to effect carcinogenesis.
d)
The first hit is insufficient to cause enough damage to cause a mutation.
Question 6 (0.5 points) Question 6 Saved
Chronic inflammation causes cancer by:
Question 6 options:
a)
Increasing vasodilation and permeability that alter cellular response to DNA damage
b)
Liberating lysosomal enzymes when cells are damaged, which initiates mutations
c)
Releasing compounds such as reactive oxygen species that promote mutations
d)
Increasing the abundance of leukotrienes that are associated with some cancers
Question 7 (0.5 points) Question 7 Saved
What is the consequence for cells when the functioning TP53 gene is lost as a result of mutation?
Question 7 options:
a)
Cells undergo apoptosis.
b)
Cells escape apoptosis. [Show Less]