Acid Base ABG’s
As pH goes, so does my Pt! Except for K
pH and HCO3 in same direction Metabolic
pH and HCO3 in different direction: Respiratory
pH
... [Show More] ↓ Pt goes ↓ (HR, RR, all vitals) K goes ↑ hypoexcitable
pH ↑ Pt goes ↑ K goes ↓ hyperexcitable
Except for K – it does the opposite
pH ↑ : Alkalosis
Seizures, hyperactivity, borborgygmi (↑BS)
Kausmal breathing = MacKausamal (Metabolic Acidosis breathing)
Causes of imbalance:
1. Is lung affected?
a. Yes-Respiratory
2. Is pt overventilating or underventilating?
a. Over-alkalosis
b. Under-acidosis
3. Not the lung?
a. Then it is Metabolic
4. If pt has prolonged vomiting or suctioning
a. Alkalosis
5. If you don’t know: it’s probably metabolic acidosis (It’s super common)
Alcoholism
Psychological
#1 problem psychologically in alcoholism and all other abusers is denial
Denial-refusal to accept the reality of a problem
o Treat denial by confronting
o Differentiate what they say versus what they doMark Klimek Audio Notes 2
DO NOT confuse confrontation with aggression (attacks the person)
Questions about staff problem interactions: Never choose YOU, choose I
Denial is okay in loss/grief
o Treat this denial with support-Do NOT confront
Denial Anger Bargaining Depression Acceptance
#2 problem dependency/codependency
o Dependency-abuser gets significant other to do things for them
o Codependency-positive self esteem significant other receives from doing things for the
abuser
o Treat by setting limits and enforce them, say no
Manipulation-abuser gets significant other for to do things them that is not in the best interest of the
SO
o Interest and harmful
o If what being asked to do is neutral-dependency
o If what being asked is harmful or not in best interest-manipulation
o Treat manipulation by setting limits and enforce, say no
Wernicke’s and Korsakoff
o Wernickes’-encephalopathy induced by vit B1/ thiamine deficiency
o Korsakoff-psychosis induced by vit B1/ thiamine deficiency
Primary symptom- amnesia with confabulation
Redirect pt to other things
Preventable-take vitamin B1/thiamine
Arrestable-take vitamin B1/thiamine
Irreversible
Antabuse (disulfiram) and Revia (naltrexone)
o Aversion therapy
o Onset: 2 weeks, Duration 2 weeks
o Pt teaching
avoid all forms of alcohol-mouthwash, aftershave, perfumes/colognes/ insect
repellants, OTC ending with elixir, alcohol based hand sanitizer, uncooked icing
DO NOT pick red wine vinaigrette
Overdose and Withdrawal
o Every abused drug is either upper or downer
o 1. Is drug upper or downer?
Upper: caffeine, cocaine, pcp/lsd, methamphetamines, Adderall (amphetamine)
Things go up: euphoria, tachycardia, restlessness, irritability, borborygmic,
diarrhea, hypereflexia 3+ or 4+, seizures (have suction at bedside)
Downer: If not upper, it is a downer
Things go down: lethargic, bradycardia, respiratory arrest (have ambu-bag
at bedside)
o 2. Overdose or withdrawal?
Overdose/intoxication-Overdose on an upper- everything goes up
Overdose downer- everything goes down
Withdrawal downer-everything go up
Wthdrawal upper-everything go downMark Klimek Audio Notes 3
Drug Addiction in Newborns
o Always assume intoxication not withdrawal at birth (before 24 hours)
Alcohol withdrawal syndrome vs delirium tremens (DT)
o Every alcoholic goes through alcohol withdrawal after 24 hr of not drinking, only minority go
through DT (72 hrs)
o Alcohol withdrawal-not life-threatening, not a danger to self or others
o DT-life-threatening, danger to self and others
AWS DT
Regular diet NPO; clear liquids
Semi-private anywhere Private, near nurse’s station
No restraints Restricted bedrest (bedpans, urinals)
Must be restrained (vest or 2 point lock
leather)
Antihypertensive/tranquilizer/Vitamin B1 Antihypertensive/tranquilizer/Vitamin B1
Ventilators
High Pressure Alarm
Obstruction-Increased resistance to airflow
o Kinks (unkink)
o Water condensation (open system and drain tubing)
o Mucous secretions in airway (TCDB, suction)
Low Pressure Alarm-↓ Resistance – machine finding job too easy
Disconnected
o Main tubing (reconnect)
o Oxygen sensor (reconnect)
If tube goes lower than pt level – contaminated
Ventilator overventilating pt can result in resp. alkalosis
Ventilator underventilating pt can result in resp. acidosis
Amino Glycosides
A Mean Old Mycin
Amino Glycosides only treat Mean old Infections!
Serious, resistant, gram-negative, life-threatening
True mean old Mycins don’t have “Thro”
If it has “Thro” – Thro it away!
Ex: Zithromycin , erythromycin, clarithromycin
Mean Old Mycins (mice) destroy ears (ototoxicity) and kidneys (nephrotoxicity)Mark Klimek Audio Notes 4
Must check Creatinine (0.6 -1.3) for Nephrotoxicity – NOT urine output
Check hearing, tinnitus, vertigo, dizziness
8 Toxic to Cranial nerve 8 (vestibulocochlear) give q8h, IM/IV
Mean Old Mycins do NOT get absorbed – they go in and out and sterilize/clean
Hepatic (encephalopathy)coma-reduce ammonia levels. Oral mycins redcues ammonia
PO Mean Old Mycins are for bowel sterilizing
NeoMYCIN
KanoMYCIN
Who can sterilize my bowel?? NEO KAN!
Drawing TAP Levels (Peak and Trough)
For drugs that have a narrow therapeutic window/level and are toxic
Digitalis
Route determines TAP – Not the drug [Show Less]