T or F. Beyond use date must be applied to each compounded product using USP 795 guidelines for Nonaqueous Liquids and Solid formulation and for
... [Show More] Water-containing Formulations. correct answer: True
Which of the following is considered with Non-Sterile Preparation? A. USP 795 B. USP 797 correct answer: A
Labels on Pharmacy-compounded products - Expiration Dates (Beyond Use Dates) correct answer: * Water containing oral formulations *
> The beyond use date is no later than 14 days when stored at controlled cold temperature
* Water containing topical/dermal/mucosal liquid and semisolid formulations *
> The beyond use date is no later than 30 days
* Nonaqueous formulations*
> The beyond use date is no later than the time remaining until the earliest expiration date of any API (use no later than 25% of time of this api) or 6 months, whichever is earlier
T or F. For capsules, the label must include mcg or mg/capsule? correct answer: True - Does not require for tablet
T or F. You can rinse compounding equipment with tap water? correct answer: False - you can only rinse Purified water for rinsing equipment
What is the best certified sterile compounding environment for injectable product? Which ISO? correct answer: ISO class 5 (class 100) laminar air flow hood within ISO class 7 (class 10,000) clean room * with positive air pressure * differential relative to adjacent areas.
ISO class 5 (class 100) clean room with positive air pressure differential relative to adjacent areas or a barrier isolator that provides a ISO class 5 (class 100) environment for compounding
T or F. Liquids in a container curve up, therefore measure at the top of the meniscus. correct answer: False. Must measure at the bottom of meniscus
What is the difference between glass and Wedge-wood/Porcelain(ceramic) Mortar and Pestle? correct answer: wedge-wood or porcelain is used commonly and is best for reducing particle size of dry powders and crystals
Glass is used for liquids or chemical that are oily or that will stain to the porcelain
T or F. It is safe not to use ointment paper to prepare creams and lotions because these two formulation have the highest content of water. Water content will cause the paper to moisten, and possibly tear. correct answer: True. we can use Glassine weighing paper
Which of the following levigating agents are the best to prepare aqueous systems (O/W dispersions)?
A. Glycerin B. Mineral oil C. Castor oil D. Cottonseed oil E. Tween 80 correct answer: A. Glycerin
> Rest are good levigating agents used to prepare oleaginous systems (W/O)
> Additional agents used as levigating agents to prepare aqueous systems consist of Propylene glycol, polyethylene glycol 80
Sometimes heat is used to mix things easier, but it lead to over-heating which produce undesired chemical-reactions. What is the best way to prevent over-heating? correct answer: A water bath will help prevent over-heating
Fill in the blank
........................ refer to a compound prepared without a specific formula (not from an official compendium) and made specifically to fill the needs of an individual patient correct answer: Extemporaneous
Fill in the blank
...................... a single agent that is used to soften and smooth the skin. A moisturizer is sometimes referred to as ................, but the term ............ is used for single agent, and moisturizers often have coloring, scents, and other ingredients added correct answer: Emollients
Fill in the blank
Oil in water , or water in Oil is example of ....... correct answer: Emulsions
Fill in the blank
............ Is used to stabilize the emulsion. ........... are usually surfactants (wetting agents) that reduce the surface tension between the two liquids so that the two different substances can move close to each other but they will not be mixed together correct answer: Emulsifiers
What is the difference between Continental or dry gum method and English, or wet gum method? correct answer: Both have same ingredients (oil, purified water and gum (such as acacia) in the ratio of 4:2:1 but the order of mixing is different.
Dry method: gum is mixed rapidly with oil then water added all at once
Wet method: gum is dissolved in water first, then oil is slowly added
What you know about HLB (hydrophilic-Lipophilic balance) number? correct answer: #s range from 0-20 [Show Less]