Biochemistry C785 EXAM
]where does transcription start - ANSWER ==at the 5' end
translation - ANSWER ==the production of protein by the
... [Show More] ribosome using the sequence of mRNA as a template
silent mutations - ANSWER ==result in no change in the amino acid sequence
missense mutation - ANSWER ==changes in a single base pair in a codon such that the codon now encodes a difference amino acid
nonsense mutation - ANSWER ==changes in a base pair in a codon to a STOP codon that terminates translation
frameshift mutations - ANSWER ==disrupts the coding of a protein because there is either an insertion or deletion
single damaged nucleotide repaired with - ANSWER ==base excision repair
multiple damaged nucleotides - ANSWER ==nucleotide excision repair
mistakes in replication (mismatches) - ANSWER ==mismatch repair
DNA polymerase proofreading - ANSWER ==
double stranded breaks repair - ANSWER ==homologous recombination
nonhomologous end joining - ANSWER ==
how is red-green color blindness inherited - ANSWER ==x-linked recessive condition
heat denatures what - ANSWER ==hydrophobic interactions
changes in pH denatures what - ANSWER ==ionic and hydrogen bonds
high salt concentrations denatures what - ANSWER ==ionic and hydrogen bonds
reducing agents denatures what - ANSWER ==disulfide bonds
how many dna copies are created after the completion of 4 PCR cycles - ANSWER ==16
What is the function of DNA polymerase in PCR - ANSWER ==recognizes the primers and uses the available dNTPs to replicate the DNA sequence
What allows a gene to have an increased expression - ANSWER ==more space between the nucleosomes; in other words, they are not packed too closely together
what occurs during the process of alternative splicing of mRNA - ANSWER ==alternative combinations of eons within the same gene are linked together by getting rid of introns
what is recombination - ANSWER ==repairing the damaged chromosome/DNA with a homologous chromosome [Show Less]