ATI TEAS 7 Biology Review.
Macromolecules:
Carbohydrate, Lipid, Nucleic Acid, Protein, Enzyme
Carbohydrate: Sugars and starches which body breaks down
... [Show More] to glucose
● Structural function: cellulose and chitin
● Energy storage: amylose, amylopectin, glycogen
● Recognition molecules: glycoproteins and glycolipids
Lipids: Fatty acids and their derivatives that are soluble inwater
● H and C and main components
● Fats
● Hydrophobic- thus help separate aqueous compartments
● Store energy (fats, oils, adipose)
Protein: Molecules composed of amino acids joined by peptide bonds
● Monomer: amino acids (amino group + carboxylic acid)(20 types)
● Keratin and Collagen (hydrophobic)- not soluble in water, found in structural protein
● Globular proteins are hydrophilic (hemoglobin, antibodies, enzymes)
● Function as transport carries or signal transfer
Nucleic Acids: Long molecules made of nucleotides; DNA and RNA
● DNA stores genetic material
● Chromosomes
● RNA is a messenger (mRNA) also rRNA and tRNA
Enzymes: Class of protein that catalyze biochemicalreactions
● Not consumed in reaction
● Speed up reaction by lowering activation energy
● Exergonic: release energy
● Endergonic: require energy
● Energy is supplied and released as ATP
● Lock and Key (substrate must fit into enzymes active site)
DNA and RNA
DNA: macromolecule that contains coded instructions for the body to
produce proteins
● Nucleotide: the building block of DNA andRNA
● Nitrogenous Base: Adenine, Thymine, Guanine, andCytosine
● Purines: Adenine and Guanine
● Pyrimidines: Thymine and Cytosine
● Codon: Agroup of 3 nitrogenous bases used to synthesize amino
acids (Synthesized from RNA during TRANSLATION)
● Hydrogen Bonds: Connect a Purine to a Pyrimidine (A-T) and (C-G). Non-covalent, weak.
o RNA: Uracil replaces Thymine
● Double Helix structure
● Coded or read 5'→3'
● Sugar(pentose)-Phosphate backbone (deoxyribose and phosphate group- bound to 4 oxygen
atoms)
DNA Replication
DNA Helicase: Unzips and Unwinds DNA strand
DNA Primase: Generates RNA Primer. Act as a template for starting point of DNA Replication
DNA Polymerase: Synthesize new DNA molecules by adding nucleotides to leading and lagging DNA
strands in 5'→3' direction
Topoisomerase: Prevents supercoiling
DNA Ligase: Joins DNA fragments together by forming phosphodiester bonds between nucleotides
Okazaki Fragment: Short, newly synthesized DNA fragments that are formed on the lagging strand
Single Strand Binding Protein: Stabilize structure during replication
Leading Strand: Replicated continuously in the 3' to 5' direction
Lagging Strand: Replicated discontinuously in short sections [Show Less]