Question:
Which medication is NOT a brand name for acetaminophen?
Mapap
Cetafen
Aleve Correct
Feverall
Explanation:
Brand names for acetaminophen
... [Show More] include Mapap, Cetafen, FeverAll and Tylenol. Aleve is
the brand name for naproxen sodium.
Question:
To treat low back pain in a patient for whom nonsteroidal anti-inflammatory drugs
(NSAIDs) are contraindicated, the recommended therapy is:
acetaminophen (Tylenol). Correct
ibuprofen (Motrin).
cyclobenzaprine (Amrix).
tramadol (Ultram).
Explanation:
To treat low back pain in a patient for whom nonsteroidal anti-inflammatory drugs
(NSAIDs) are contraindicated, the recommended therapy is acetaminophen (Tylenol). A
nonsteroidal anti-inflammatory drug (ibuprofen) is recommended as initial therapy for
the treatment of back pain. The trial should be short-term, usually 2 to 4 weeks.
Acetaminophen is a reasonable option for initial therapy in patients with
contraindications to NSAIDs.
Question:
The patient at highest risk for side effects from cyclobenzaprine (Amrix) is a:
20-year-old man with spasticity and a history of seizures.
40-year-old woman diagnosed with diabetes mellitus.
50-year-old woman with a history of asthma.
70-year-old man diagnosed with benign prostatic hypertrophy. Correct
Explanation:
Cyclobenzaprine (Amrix) is identified in the Beers Criteria as a potentially inappropriate
medication and should be to be avoided in patients 65 years and older (independent of
diagnosis or condition). This is because most muscle relaxants are poorly tolerated in
older adults due to anticholinergic effects. Amrix may also increase sedation and
fracture risk. Cyclobenzaprine (Amrix) has strong anticholinergic properties. In addition,
efficacy is questionable at doses tolerated by geriatric patients. Although
cyclobenzaprine may lower the seizure threshold, it is not a contraindication. The
provider should weigh the risks versus the benefits.Question:
When assessing a patient with suspected acetaminophen (Tylenol) overdose, the time of
ingestion can be confirmed by checking:
acetaminophen levels now and in 4 hours. Correct
baseline acetaminophen levels.
liver function studies now and in 4 hours.
acetylcysteine levels.
Explanation:
When assessing a patient with suspected acetaminophen (Tylenol) overdose, the time of
ingestion can be confirmed by checking serum acetaminophen levels at the time of
presentation and again in 4 hours. This is especially important if the time of
acetaminophen ingestion is unknown.
Question:
A patient with severe osteoarthritis is complaining of a pain exacerbation due to
weather change. Ketorolac should be avoided in this patient due to a drug-drug
interaction with:
diclofenac (Zorvolex). Correct
lisinopril (Zestril).
omega-3 fatty acids.
spironolactone (Aldactone).
Explanation:
The concomitant use of ketorolac (Toradol) and other nonsteroidal anti-inflammatory
drugs (NSAIDs), such as diclofenac (Zorvolex), is absolutely contraindicated due to
enhancement of the adverse/toxic effect of NSAIDs. Therapy should be monitored in the
presence of ACE inhibitors, omega-3 fatty acids and potassium-sparing diuretics, but it
is not contraindicated.
Question:
The half-life elimination of colchicine (Colcrys), used in the treatment of gout, is
approximately:
8 hours.
15 hours.
30 hours. Correct
48 hours.
Explanation:
The half-life elimination of colchicine (Colcrys) in an otherwise healthy person is about
27-31 hours. Colchicine is an alkaloid indicated for the treatment of acute gout and for
the prophylactic treatment of gout. It is approved for use in patients aged 16 and older
for gout prophylaxis.
Question:
Dantrolene (Dantrium) reduces skeletal muscle spasticity by:
interfering with the release of potassium from the sarcoplasmic reticulum.
interfering with the release of calcium from the sarcoplasmic reticulum. Correct
centrally blocking action potentials.blocking the actin-myosin binding site in striated muscle.
Explanation:
Dantrolene (Dantrium) reduces skeletal muscle spasticity by acting directly on skeletal
muscle and interfering with release of calcium ion from the sarcoplasmic reticulum. It is
classified as a peripherally-acting muscle relaxant. It is not a centrally-acting muscle
relaxant.
Question:
Which formulation of naproxen would result in fewer GI side effects?
Naprosyn
Naprosyn suspension
Anaprox DS
EC-Naprosyn Correct
Explanation:
EC-Naprosyn dissolves in the small intestine rather than in the stomach. Fewer GI side
effects would be expected with this medication. However, this results in delayed
absorption and thus delayed relief of acute pain could also be anticipated. The other
listed forms of naproxen are absorbed in the stomach and produce a greater risk of GI
upset.
Question:
Salicylates, such as aspirin,:
prevent the formation of clots by affecting blood coagulation.
inhibit vitamin K epoxide reductase and prevent blood clots.
inhibit the synthesis of prostaglandin in the process of inflammation. Correct
block the activity of clotting factor X and prevent blood clots [Show Less]