Hegar's sign - Softening of lower uterine segment
Chadwick's sign - Bluish color of cervix and vagina at 6-8 weeks
Goodell's sign - Softening of
... [Show More] cervix at 4+ weeks
Lipids in chronic inactivity - Low HDL
Lipids in under- or untreated hypothyroidism - Elevated total cholesterol, TG, and LDL
Lipids in chronic renal insufficiency - Elevated total cholesterol and TG
Lipids in alcohol abuse - Elevated TG, HDL, and LDL
Vaccines with live attenuated viruses - MMR, varicella, flu-mist(intranasal), Zostavax
Drugs of choice for abdominal infection - Beta lactams + metronidazole (most common); fluoroquinolones
Drugs of choice for urinary tract infection - Fluoroquinolones (except moxi), TMP-SMX, fluconazole, b-lactams, nitrofurantoin, fosfomycin if pt has many allergies
Drugs of choice for pulmonary infections - Macrolides, resp fluoroquinolones, b-lactams, doxycycline (MRSA, atypical coverage)
Drugs of choice for skin and soft tissue infections - MRSA: TMP-SMZ, doxycycline, clindamycin; b-lactams
Drugs of choice for MRSA - Vancomycin, daptomycin , linezolid, TMP-SMZ, doxycycline, ceftaroline
Macrolide drugs - Erythromycin, clarithromycin, azithromycin
Macrolide AEs - GI, QT prolongation
Tetracycline uses - MRSA, rocky mtn spotted fever, atypicals (mycoplasma pneumonia, chlamydia), spirochetes (Lyme), h.pylori
Tetracycline AEs - GI, teeth, hepatic dysfunction, photosensitivity
Fluoroquinolone drugs - Ciprofloxacin, levofloxacin, moxifloxacin
Fluoroquinolone uses - UTI (cipro or levo), atypicals (mycoplasma, legionella)
Fluoroquinolones and dairy or vitamins - Take 2 hrs before or 4 hours after (decrease concentrations)
Metronidazole (Flagyl) uses - C. Diff, vaginitis
Metronidazole AEs - GI, peripheral neuropathy, disulfiram reaction
Nitrofurantoin uses - UTI -not pyelonephritis due to no systemic absorption
Nitrofurantoin AEs, contraindications - Pulmonary fibrosis, contraindicated in CrCl <60 (excludes many elderly)
Aminoglycoside drugs - Gentamycin, tobramycin
Aminoglycoside uses - Atypical coverage, resistant infections, tobramycin for CF only
Aminoglycoside AEs - Ototoxicity (irreversible), nephrotoxicity (reversible)
Aminoglycoside monitoring - Renal dose adjust, hearing test, drug level monitoring
Antifungals (azoles) - Fluconazole, itraconazole
Itraconazole interactions - Acid suppressive therapies
Fluconazole dose adjust - Renal
Antifungal AEs - GI, QTc prolongation (fluconazole)
Antifungal drug interactions - QT prolongation meds, warfarin
Anti-infectives not for pregnant - Tetracyclines, TMP-SMZ
TMP-SMZ coverage - G+, G-, MRSA, Protozoa (toxoplasma gondii), fungus (pneumocystis jirovecii), poor anaerobic activity
TMP-SMZ AEs - Sulfa allergy, photosensitivity, hematologic (anemia, leukopenia, thrombocytopenia)
TMP-SMZ on renal function - Dose adjust in renal impairment, false elevation in serum Cr
TMP-SMZ drug interactions - Warfarin
Gram + only coverage - Clindamycin, linezolid, vancomycin, daptomycin
Gram - only - Monobactams (aztreonam), penicillin VK [Show Less]