A risk factor associated with the use of metformin in the treatment of diabetes is lactic acidosis. Acidosis is associated with [a decrease] in blood pH,
... [Show More] due to [an increase] in the concentration of hydrogen ions (H+). Given this change in blood pH, hemoglobin is more likely to [release] oxygen.Correct Answers: Acidosis is associated with a decrease in blood pH, due to an increase in the concentration of hydrogen ions (H+). Given this change in blood pH, hemoglobin is more likely to release oxygen.
A small segment of Kevin's green opsin gene is shown below. What would be the resulting mRNA sequence?
Kevin's opsin gene at nucleotide positions 936 to 941.
5'-G.C.C.T.A.G-3' (coding strand)
3'-C.G.G.A.T.C-5' (template strand)
c. 5'-GCCUAG-3'Correct Answers: This sequence is the same as the coding sequence, and the "T" bases have been replaced with "U", as is found in RNA.
A substrate binds to an enzyme at a specific site, referred to as a(n)_________________.
b. Active siteCorrect Answers: The active site of an enzyme is the site where the substrate specifically binds to the enzyme and the reaction is carried out.
Acetyl-CoA, a central molecule in metabolism, is produced in the mitochondrial matrix. However, it is used for the synthesis of fatty acids in the cytosol. The transport of the acetyl-CoA from the matrix to the cytosol occurs by the conversion of acetyl-CoA to_______________.
a. citrateCorrect Answers: Acetyl-CoA combines with oxaloacetate to produce Citrate. Note that citrate is the first product produced in the citric acid cycle by the same reaction. Cells have the ability to mobilize citrate across the mitochondrial membrane. Thus, acetyl-CoA moves out of the mitochondria to the cytosol in the form of citrate. Once in the cytosol, the citrate is converted back to oxaloacetate and acetyl-CoA, and acetyl-CoA is utilized in fatty acid synthesis. [Show Less]