Review Test Submission: Midterm
Exam - Week 6
Question 1
What is the strongest established risk factor for bipolar disorder? Family
... [Show More] History
Response Feedback: “The strongest established risk factor for BPD is a family history of BPD.”
Question 2
Which of the following medications are known as selective serotonin re-uptake inhibitors (SSRIs)?
i. Nortriptyline
ii. Citalopram
iii. Duloxetine
iv. Fluoxetine
v. Venlafaxine
vi.
Question 3
Which disease state of a non-adherent patient is at greater risk for substance use, violence, and victimization as
well as worse overall quality of life? Schizophrenia
Response
Feedback:
“Moreover, non-adherent patients with schizophrenia are at greater risk for substance
use, violence, and victimization as well as worse overall quality of life.”
Question 4
Patient is a 72-year-old male with a past medical history significant for atrial fibrillation and COPD with a new
diagnosis of major depression disorder. Based on his comorbid conditions, what antidepressant would you
recommend as first-line?
Response
Feedback:
(Options C & D are both TCA antidepressants and, based on the patient’s age and comorbid
conditions, a TCA would likely result in more side effects, such as increased fall risk due to
potential for orthostatic hypotension and anticholinergic-related side effects. In addition,
patient has a history for cardiac abnormalities due to A. fib diagnosis - TCAs result in
electrocardiographic changes in susceptible individuals, therefore, would likely avoid. Choice
B is used more for ADHD purposes than as an antidepressant)
Page numbers used: Page 39 for TCA side-effect profile
Question 5
Which of the following is an appropriate strategy for managing treatment-resistant depression?
Use both SSRI and SNRI
Question 6
Which of the following medications is best to AVOID in maintenance treatment of bipolar disorder and why?
Response
Feedback:
“As noted previously, antidepressants may contribute to an increase in mood episode
frequency.”
Question 7
With second-generation antipsychotics, what is the main side effect that requires frequent monitoring?
Response
Feedback:
table 7-6 & page 80, table 7-7; Page 78: “However, attention over the past decade has
focused on effect of second-generation antipsychotics on glucose metabolism and lipids and
associated metabolic syndrome.”
Question 8
Which amino acid is involved in the synthesis of both norepinephrine and dopamine?
Question 9
An 81-year-old male comes to your clinic today complaining of dry mouth, blurred vision, and constipation. He
has a past medical history significant for hypertension, heart failure, and depression. Of the following
medications, which one is likely contributing to these side effects?
Response
Feedback:
Only TCA is listed with most anticholinergic effects; Page 39 for TCA side effect profile:
“dry mouth, blurred vision, constipation, urinary hesitancy, tachycardia, memory
difficulties, and ejaculatory difficulties”
Question 10
Which medication has been studied and recommended in patients with a social anxiety disorder who also suffer
from an alcohol use disorder?
Response
Feedback:
“Suggested that treatment with the SSRI paroxetine decreased the anxiety and may have
reduced the alcohol use as well”
Question 11
M. B. was just diagnosed with Generalized Anxiety Disorder and pharmacotherapy is needed. Which of the
following would be a first-line treatment option for M. B.?
i. Duloxetine
ii. Quetiapine
iii. Diazepam
iv. Escitalopram
v.
Response
Feedback:
“As is true for panic and the other anxiety disorders, the SSRIs and SNRIS are generally
considered first-line agents for the treatment of GAD because of their favorable side effect
profile….”
Question 12
The serotonin system is involved in m [Show Less]