Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice 10e,
Geralyn Frandsen
Chapter 1: Introduction to Pharmacology
Multiple Choice
1. A
... [Show More] woman has been prescribed paroxetine hydrochloride, which is an antidepressant agent
administered in pill form. The medication is administered for her obsessive-compulsive disorder.
This medication will produce which of the following effects?
A) Curative
B) Systemic
C) Local
D) Parenteral
Ans: B
Chapter: 1
Client Needs: D-2
Cognitive Level: Comprehension
Difficulty: Moderate
Integrated Process: Nursing Process
Objective: 1
Page and Header: 4, Introduction
Feedback: Drugs that produce systemic effects are taken into the body, circulated through the
bloodstream to their sites of action in various body tissues, and eventually eliminated from the
body. Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride
will control the symptoms but not cure the disorder. Drugs with local effects, such as sunscreen
and local anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not
administered parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or
intravenously.
2. A patient has been prescribed an antibiotic. This medication is a naturally occurring substance
that has been chemically modified. What is another name for this type of medication?
A) Synthetic drug
B) Semisynthetic drug
C) Biotechnology drug
D) Prototype drugAns: B
Chapter: 1
Client Needs: D-2
Cognitive Level: Comprehension
Difficulty: Moderate
Integrated Process: Nursing Process
Objective: 1
Page and Header: 4, Drug Sources
Feedback: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that
have been chemically modified. Synthetic drugs are more standardized in their chemical
characteristics, more consistent in their effects, and less likely to produce allergic reactions.
Biotechnology drugs involve manipulating DNA and RNA and recombining genes into hybrid
molecules that can be inserted into living organisms. Prototype drugs are the first drug of a
particular group to be developed.
3. A patient is administered morphine. Morphine is a prototypical drug that can be classified in
different ways. Which of the following classifications applies to morphine?
A) Central nervous system depressant
B) Central nervous system stimulant
C) Anti-inflammatory
D) Antihypertensive
Ans: A
Chapter: 1
Client Needs: D-2
Cognitive Level: Knowledge
Difficulty: Easy
Integrated Process: Nursing Process
Objective: 3
Page and Header: 4, Drug Classifications and Prototypes
Feedback: Drugs are classified according to their effects on particular body systems, their
therapeutic uses, and their chemical characteristics. For example, morphine can be classified as a
central nervous system depressant and a narcotic or opioid analgesic. A central nervous system
stimulant increases attention and raises mood. An anti-inflammatory agent decreases
inflammation at the site of tissue or joint inflammation. An antihypertensive agent reduces blood
pressure.
4. A patient is administered amoxicillin (Amoxil). The generic name of this medication indicates
that it belongs to which drug group?A) Selective serotonin reuptake inhibitors
B) Diuretics
C) Penicillins
D) ACE inhibitors
Ans: C
Chapter: 1
Client Needs: D-2
Cognitive Level: Comprehension
Difficulty: Easy
Integrated Process: Nursing Process
Objective: 2
Page and Header: 4, Drug Names
Feedback: The generic name often indicates the drug group (e.g., drugs with generic names
ending in ìcillinî are penicillins). Selective serotonin reuptake inhibitors are medications that
have antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics are
medications that increase urine output; diuretic is a broad classification, not a generic name.
ACE inhibitor is the broad classification for the angiotensin-converting enzyme inhibitors, not
the generic name. [Show Less]