Pharmacology 1st Semester Nursing STLCC Exam With Complete Solution 2024.
At what phase during drug evaluation does the drug first hit the
... [Show More] clinical
market?
A. Preclinical Trial
B. Phase I
C. Phase II
D. Phase III
E. Phase IV - ANSWER D. Phase III
During Preclinical Trials the chemical is tested in a lab on animals to
determine its therapeutic and toxic effects.
During Phase I the drug is then tested on human volunteers that are typically
compensated.
During Phase II the drug is tested on patients that the drug is designed to
treat and is more selective than Phase I.
During Phase III the drug will first hit the clinical market.
During Phase IV the drug is continued to be evaluated and monitored.
What an example of a Generic Drug name? (Select all the apply)
A. Tylenol
B. Ibuprofen
Pharmacology 1st Semester Nursing STLCC Exam
With Complete Solution 2024
C. Acetaminophen
D. Excedrin - ANSWER B. Ibuprofen
C. Acetaminophen
Tylenol and Excedrin are examples of brand names
How long is a standard patent on a drug once it hits the market before other
drug companies can start to produce the drug?
A. 2 years
B. 3 years
C. 5 years
D. 10 years - ANSWER C. 5 years
What is the term used to describe how a drug moves through the body?
A. Pharmacotherapeutics
B. Bioavailability
C. Biotransformation
D. Pharmacokinetics - ANSWER D. Pharmacokinetics
Pharmacotherapeutics is a branch of pharmacology that uses drugs to treat,
prevent, and diagnose disease.
Bioavailability is the concentration of a drug that actually reaches the
systemic circulation
Biotransformation is the alteration of a drug structure, changing a drug from
it's original form to an activated form
Pharmacokinetics refers to the action of a drug as it moves through the body
kinetics meaning movement
What organ in the body does biotransformation take place?
A. Kidney
B. Liver
C. Brain
D. Small intestine - ANSWER B. Liver
The liver is where the body does a good portion of it's metabolism
The kidney is the most common place of excretion in the body. Where else
can the body excrete from? (Select all the apply)
A. Skin
B. Saliva
C. Lungs
D. Bile
E. Feces - ANSWER All of the listed the body excrete from
Which can pass through the blood-brain barrier?
A. Drugs that are fat soluble
B. Drugs that are water soluble - ANSWER A. Drugs that are fat soluble
This is why any infection is the brain is very dangerous, antibiotics are water
soluble and are unable to pass through that barrier.
How do drugs travel through the bloodstream?
A. Attached to a protein
B. Attached to platelets
C. Freely through the blood
D. Freely through the lymph - ANSWER A. Attached to a protein
ADDITIONAL INFO
Drugs are either loosely or tightly bound to a protein. Loosely bound drugs
act quickly and in turn are excreted quickly while tightly bound drugs are the
extended released type drug that release a small amount overtime. [Show Less]