Pharm test 3 Maryville NURS 615 Questions and Answers Latest
How do antigout medications work?
{{Ans- by inhibiting the infiltration and phagocytosis
... [Show More] of leukocytes, thus decreasing the breakdown of uric acid to urate crystals.
Deposition of urate crystals causes
{{Ans- pain and inflammation
What is Colchicine {{Ans- anti-gout medication
how does Colchicine work? {{Ans- Works by inhibiting inflammation, reducing pain and swelling
common side effects of Colchicine
{{Ans- GI problems (diarrhea) use with caution in elderly
Also can cause blood dyscrasias & abdominal pain
patient education with Colchicine
{{Ans- Can be given with food & milk to decrease GI issues
Avoid beer, ale, & wine: may cause gout attack
Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
Low dose of Colchicine
{{Ans- Low dose colchicine is 1.2mg followed by 0.6mg one hour later or 1.8 milligrams total
High dose of Colchicine
{{Ans- high dose colchicine is 1.2mg followed by 0.6mg every four to six hours; or 4.8mg total.
Difference between high dose and low dose Colchicine
{{Ans- The difference between the two is low dose is as effective as high dose with a lower side effect profile.
Lab values to monitor with Colchicine
{{Ans- Check renal function test, BUN, Creatine
Patient education with Colchicine
{{Ans- Almost always causes some degree of diarrhea, make sure patients are aware of this side effect
Patient education with Febuxostat (Uloric) {{Ans- Gout may worsen with therapy initially
Dietary changes to decrease gout attacks and uric acid deposits.
{{Ans- Avoid beer, ale, & wine
Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
What is not a first line for pain medication? {{Ans- Narcotics
Recommendations for pain treatment
{{Ans- You want to start with NSAIDs first and then work your way up from there.
types of Corticosteroid treatment {{Ans- Prednisone, Cortisone, Dexamethasone
how do Corticosteroids work?
{{Ans- Suppress the inflammatory & immune systems by inhibiting the synthesis of chemical mediators.
what are the chemical mediators that Corticosteroids work on?
{{Ans- Prostaglandins, leukotrienes, & histamines
Corticosteroids and inflammation
{{Ans- Decreases inflammation which decreases swelling, warmth, redness, & pain.
Uses for corticosteroid treatment
{{Ans- Addison's disease, hormone replacement, cancer therapy
SLE, arthritis, IBD, & to suppress graft rejection [Show Less]