Oral Pathology Final Exam - Questions and Answers What is a leukoedema? A blue/grey/white mucosa that blanches Note: It disappears when stretching. It is
... [Show More] mostly bilateral. There is no treatment A patient presents with bilateral, grayish-white lesion of the buccal mucosa. This lesion disappears when the mucosa is stretched. What is the most likely condition? Leukoedema What is associated with chronic myelogenous leukemia? Philadelphia chromosome 22 Note: A chromosomal translocation A patient shows up with a kid that has bleeding gums, problems healing, and discomfort. What is the most likely condition? Leukemia What is the most common type of leukemia in children? Acute lymphatic leukemia Note: lymphoblastic A patient had erythematous and gingival enlargement over past 5 weeks. There is increased report of bruising on the body. What is the most likely cause? Acute leukemia, specifically acute lymphatic leukemia A 6-year-old patient has acute lymphatic leukemia. Her deciduous molar has large carious lesion and furcation lucency. How will you treat this patient? Extraction What is a salivary gland tumor? A benign tumor Note: Parotid glands are still where most malignant salivary gland tumors start. Major salivary glands consist of parotid, submandibular, and sublingual glands. Minor salivary glands include small mucus-secreting glands located throughout the palate, nasal, and oral cavity. What is the most common salivary gland tumor? Pleomorphic adenoma Note: A benign mixed tumor What is the most common malignant major salivary gland tumor? Mucoepidermoid carcinoma What is the most common malignant minor salivary gland tumor? Adenoid cystic carcinoma What is an adenoid cystic carcinoma? A high grade salivary malignancy Note: Most common malignancy. Palate is the most common. It has a "Swiss cheese" microscopic pattern. It spreads through perineural spaces What is a necrotizing sialometaplasia? A minor salivary gland disease Note: It presents on the palate which is most commonly confused with carcinomas due to the ulcerated presentation. It heals without scarring. What is the most common salivary gland tumor? Pleomorphic adenoma What has the best prognosis of malignancy? Adenoid cystic carcinoma What is the most common type of gland in a pleomorphic adenoma? Minor glands of palate Note: Most common tumor of parotid gland Which of the salivary tumor glands has the best prognosis? Mixed tumor Note: Pleomorphic adenoma Where do you see peri-neural invasion? Adenoid cystic carcinoma Note: Adenoid cystic carcinoma tumor has a marked tendency to invade nerves. Peri-neural invasion is seen in about 80% of all specimens Which tumor has a Swiss cheese appearance? Adenoid cystic carcinoma What is a warthin tumor? A benign cystic tumor of the salivary glands containing abundant lymphocytes and germinal centers A warthin tumor is most common in which gland? Parotid gland What is an ameloblastoma? The most aggressive and most common epithelial odontogenic tumor Note: Occurs mostly in mandibular molar area. It is a solid, well-defined, multi cystic or polycystic lesion. It is the most aggressive kind and requires surgical excision How does an ameloblastic fibroma compare to an ameloblastoma? A younger age, slower growth, and does not infiltrate Note: Usually associated with impacted teeth What is the histology of an ameloblastoma? Stellate reticulum in bell stage Note: A stellate reticulum is a group of cells located in the center of the enamel organ of a developing tooth What can lead to an ameloblastoma? Dentigerous cyst What cyst is an ameloblastoma most likely to stem from? Dentigerous cyst What describes an ameloblastoma best? Local invasion What is the most definite way to distinguish ameloblastoma from an odontogenic keratocyst? Reactive light microscopy What shows multilucency in bone and ramus? Ameloblastoma On X-Ray, a painless, well-circumscribed radiolucency and radiopacity in the posterior mandible of an 11-year-old boy. What is the differential diagnosis? Ameloblastic fibro-odontoma Which lesion can become ameloblastomic? Dentigerous cyst A radiographic picture shows an upside down molar with lucency around the crown. What is it? Dentigerous cyst Which cyst is most likely to become neoplastic? Dentigerous What is an odontoma? A benign tumor of odontogenic origin, commonly in the mandible. Note: It starts off lucent but develops, but develops small calcification to be radio dense lesion. It can give rise to dentigerous cyst. It is divided into 2 categories: a complex odontoma (irregular calcified lesions with no distinct tooth components) and compound odontoma (identifiable tooth components) What syndrome is associated with multiple odontoma? Gardner's syndrome A picture of multiple small teeth within a radiolucency around the canine. What is the most likely condition? Compound odontoma Note: Tumor of mixed (epithelial and mesenchymal) origin is the odontoma. These calcified lesions take 1-2 general configurations. They may appear as multiple miniature or rudimentary teeth (compound odontoma). What is an adenomatoid odontogenic tumor? A tumor that arises from the enamel organ or dental lamina Note: It's mostly found in young females, maxillary, and usually associated with unerupted permanent tooth. 2/3 maxilla, 2/3 female, 2/3 in anterior jaw There is a radiolucency at the end of a tooth that looks like there might be an adenomatoid odontogenic tumor, but the patient is having symptoms [Show Less]