NURS 5334 Exam 2 Study Questions and Answers – Latest Updated 2024/2025 (Graded A+)
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WhatIareItheIbasicImechanismsIbyIwhichIneuropharmocologicIagentsIact?
o CanImodifyItheIdiseaseIprocess
o ActIatItheIsitesIofIactionsIwhichIisItheIaxonsIversusIsynapsesIandIstepsIinIsynaptic
ItransmissionIandIeffectsIofIdrugsIonItheIstepsIofIsynapticItransmission
• TransmittterIsynthesisIisItheIfirstIstepIinItransmission.IWhatIareItheIotherI4Isteps?
o Transmitterstorage, I ItransmitterIrelease, IreceptorIbinding, IandIterminationIofIthe
Itransmission
• TrueIorIFalse:INeuropharmacologicIdrugsIhaveIhighIselectivity.
o True—theInervousIsystemIusesImanyIdifferentIreceptorItypes
• InformationIneeded:
o TypeIofIreceptors—throughIwhichItheIdrugIacts
▪ AlphaIandIbeta
o Normal IresponsesItoItheIactivationIofIthoseIreceptors
▪ AgonistsIvs.Iantagonists
o WhatItheIdrugIinIquestionsIdoesItoItheIreceptorIfunction
• WhatIareItheI3IfunctionsIofIANS?
o RegulatesItheIheart
o RegulatesItheIsecretoryIglands, IsalivaIglands, Igastric, Isweat, IandIbronchial
o ItIregulatesIsmoothImuscles:Ibronchi, IbloodIvessels, Iurogenital Isystem, IandItheIGIItract
• WhatIareItheIregulatoryIfunctionsIofItheIparasympatheticINS?
o SevenIregulatoryIfunctions
▪ SlowingItheIheartIrate
▪ IncreasingItheIgastricIsecretions
▪ EmptyingItheIbladder
▪ EmptyingItheIbowel
▪ FocusingItheIeyeIforInearIvision,
▪ ConstrictingItheIpupil
▪ ContractingItheIbronchial IsmoothImuscle
o ItIalsoIregulatesItheIdigestionIofIfood, IexcretionIofIwaste, Icontrol IofIvisionIand
IconservationIofIenergy
• WhatIareItheIfunctionsIofItheIsympatheticINS?
o RegulationIofItheIcardiovascularsystem I
▪ MaintainingIbloodIflowItoItheIbrain
▪ RedistributingIbloodIandIcompensatingIforItheIlossIofIblood
o RegulationIofIbodyItemperature
▪ RegulatesIbloodIflowItoItheIskin
▪ PromotesItheIsecretionIofIsweat
▪ InducesIpiloerectionI(erectionIofItheIhair)
o ImplementationIofItheIfightIorIflightIreaction
▪ IncreaseIHRIandIBP
▪ BloodIshutsIawayIfromItheIskinIandIvisera
NURS 5334 Exam 2 Study Questions and Answers
– Latest Updated 2024/2025 (Graded A+)
2
▪ Bronchi Idilate
3
▪ PupilsIdilate
▪ UseIenergyIthatIhadIbeenIstored
• WhatIisItheIbaroreceptorIreflex?
o TheIreceptorsInearItheIheartImonitorIBPIchangesIandIsendItheIinformationItoItheIbrain
o TheIbrainIthenIactivatesItheIAutonomicINSItoIrestoreIbloodIpressureItoInormal
o WhenIBPIfalls, IthisIreflexIcausesIvasoconstrictionIandIincreasesIcardiacIoutput.
o WhenIBPIrises, IitIcausesIvasodilationIandIreducesIcardiacIoutput
• WhereIisIacetylcholineIemployed?
o MostIjunctionsIatItheIperipheral InervousIsystem
• WhereIisIepinephrineIandInorepinephrineIreleased?
o Norepinephrine—postganglionicIneurons
o Epinephrine—adrenal Imedulla
• WhatIareItheIcholinergicIreceptorsImediatedIby?IWhatIareItheIsubtypes?
o ReceptorsIthatImediateIresponsesItoIacetylcholine
o Subtypes:
▪ Nicotinic
▪ Muscarinic
• WhareIareIadrenergicIreceptorsImediatedIby?IWhatIareItheIsubtypes?
o MediateIresponsesItoIepinephrineIandInorepinephrine
o Subtypes:
▪ Alphas
▪ Betas
▪ Dopamine
• WhatIareItheIfunctionsIofIeachIadrenergic Isubtype?
o AlphaI1—vasoconstriction, IejaculationIandIcontractionIofItheIbladderIneck, IandIprostate
o AlphaI2—(locatedIinIpresynapticIjunction)—minimal Iclinical Isignificance
o BetaI1—control ItheIheart
▪ IncreaseIHR, IincreaseIforceIofIcontractionIandIvelocityIofIconductionIinItheIAV
Inode;IstimulateIreninIreleasedIinItheIkidney
o BetaI2—bronchial Idilation, IrelaxationIofItheIuterineImuscle, Ivasodilation, Iglycogenolysis
o Dopamine—dilatesIrenal IbloodIvessels
• EpinephrineIcanIactivateIall IalphaIandIbetaIreceptorsIbutInotIdopamineIreceptors
• NorepinephrineIcanIactivateIalpha1, Ialpha2, IandIbetaIreceptorsIbutInotIbeta2IorIdopamine
Ireceptors
• DopamineIcanIactivateIalpha1, Ibeta1IandIdopamineIreceptors
• MuscarinicIagonistsImimicItheIeffectsIofIacetylcholineIatImuscarinicIreceptors
• MuscarinicIantagonistsIselectivelyIbloodItheIeffectsIofIacetylcholineI(andIotherImuscarinic
Iagonists)IatImuscarinicIreceptors
• WhatIareItherapeuticIusesIofIBethanechol?
o Urinary Iretention
o Investigational IGIIuses—offIlabel IGIIreflux
• WhatIareIactionsIonIsmoothImuscle, IexocrineIglands, IandIeye?
o SmoothImuscle—
4
▪ lungIbyIcausingIconstrictionIofItheIbronchi
▪ theIGIIsystemIbyIincreasingItoneIandImotility
▪ theIbladderIbyIcontractionIofItheIdetrusorImuscle
▪ relaxationIofItheItrigoneIandIsphincter
o ExocrineIglands—increasedIsweatingIsalivation, Ibronchial IsecretionsIandIsecretionIof
IgastricIacid
o Eye—causesImiosisIandIcontractionIofItheIciliaryImuscle
• AdverseIEffects?
o Hypotension
o Abdominal Icramps
o Diarrhea
o IncreasedIsalivation
o ExacerbateIasthma [Show Less]