NR566 Week 1 Study Outline
NR 566
NR566 Week 1 Study Outline
Many questions are written to assess your clinical application of the material from the
... [Show More] textbook, in real-world scenarios.
Chapter 21: Drugs Affecting the Endocrine System
• Know the pharmacodynamics, pharmacotherapeutics clinical use, drug interactions and adverse drug reactions for:
o Biphosphonates
o Aromatase inhibitors
o Growth hormones
o Pancreatic enzymes
o Insulin
o Oral hypoglycemic agents
o Thyroid medications
• Also know:
o Bioavailability of bisphosphonate drugs and appropriate patient education
o Adverse effects associated with long-term use
o Specifics about administration and education regarding pancreatic enzymes
o Common adverse effects with aromatase inhibitors
o Drugs associated risk for bone loss which should be monitored
Chapter 33: Diabetes Mellitus
• Clinical signs & symptoms
• Risk factors & associated complications
• Diagnostic criteria
• Criteria for screening asymptomatic adults
• Differentiate between onset, peak and duration of insulin and oral hypoglycemic agents (table 33-4)
• Know treatment algorithms
• A1C treatment goal
• Calculate an appropriate daily dose of insulin for initiation of insulin therapy
• Insulin treatment algorithm for Type 1 DM
• A1C monitoring during oral or insulin diabetes management
• Correlate mean plasma glucose level according to A1C (table 33-6)
• Clinical manifestations of diabetic autonomic neuropathy
• Hypoglycemia treatment (amount of carbohydrates and examples)
• Storage of insulin
• Drug monitoring with metformin
• Antidiabetic medications associated with photosensitivity
• Antidiabetics to avoid in the elderly & why
• Improving patient compliance with diabetes treatment
• Diabetic medications to avoid when taking digoxin
• Classes of diabetes medications
• Diabetic medications with need for renal dose adjustment
• Diabetic medications associated with increased risk for genital mycotic infections
Chapter 41: Hyperthyroidism and Hypothyroidism
• Clinical signs & symptoms, risk factors, associated symptoms and diagnosis
• Time anticipated for total reversal of hyperthyroid symptoms with methimazole
• Other drugs used to provide symptomatic relief
• Routine testing with drug therapy
• Recommended dietary iodine intake
• Drugs that increase metabolism of T4
• Symptoms of hyperthyroidism and hypothyroidism
• Hyperthyroid drugs with risk for hepatic toxicity
• Bile acid sequestrants absorption and administration
• Levothyroxine administration instructions
• Differentiate between primary and secondary hypothyroidism and hyperthyroidism
NR566 Week 2 Study Outline
Many questions are written to assess your clinical application of the material from the textbook, in real-world scenarios.
Chapter 17: Drugs Affecting the Respiratory System
• Know the pharmacodynamics, pharmacotherapeutics clinical use, drug interactions and adverse drug reactions for:
o Short and long acting beta agonists
o Inhaled anticholinergics
o Xanthine derivatives
o Inhaled corticosteroids
o Nicotine replacement medications
o Tuberculosis (TB) medications
• Also know
o Precautions and testing for xanthine derivatives
Chapter 30: Asthma and COPD
• Diagnosis and classification of asthma
• Risk factors for fatal asthma attacks
• Asthma step therapy and goals of step therapy
• COPD therapy and goals of treatment
• Respiratory drug interactions with digoxin
• Patient education for treatment of asthma
• Use of oral corticosteroids in the treatment of COPD and asthma
Chapter 42: Pneumonia
• Etiology, diagnosis, classification and risk factors
• Pneumonia therapy and goals of treatment
• Common bacterial pathogens
• Clinical practice guidelines for treatment of CAP
• CAP treatment in pregnancy
• Radiologic findings during CAP treatment
• Treatment of chlamydial pneumonia
Chapter 43: Smoking Cessation
• Patient instructions for use of nicotine replacement medications
• Common side effects associated with smoking cessation therapy
• Contraindications for smoking cessation therapy
Chapter 45: Tuberculosis
• Etiology, diagnosis and risk factors
• Rationale drug selection for special populations (i.e., pregnancy and children)
• Criteria for resistant TB diagnosis
• Risk factors for fatal hepatitis with INH use
• Prophylactic treatment of TB for high risk patient
NR566 Week 3 Study Outline
Many questions are written to assess your clinical application of the material from the textbook, in real-world scenarios.
Chapter 16: Drugs Affecting the Cardiovascular & Renal Systems
• Know the pharmacodynamics, pharmacotherapeutics clinical use, drug interactions and adverse drug reactions for:
o Angiotensin converting enzyme inhibitors (ACEI)
o Angiotensin receptor blockers (ARBs
o Calcium channel blockers (CCB)
o Cardiac glycosides and antiarrhythmics
o Nitrates and peripheral vasodilators
o Anti-lipidemics
o Diuretics
• Also know:
o ACEIs & ARBs benefits in other conditions
o Dosing schedules
o Management of ACEI side effects
o Therapeutic monitoring for cardiac glycosides and antiarrhythmics
Chapter 28: Chronic Stable Angina & Low Risk Unstable Angina
• Differentiate between myocardial oxygen supply & demand
• Etiology, diagnosis and risk factors
• Grading criteria for levels of angina
• Differentiate between short & long acting nitrates
• Treatment and rational drug selection
• Understand which drugs increase myocardial oxygen supply
• Long-acting nitrate effects
• Nitroglycerine rationale for route of administration chosen
• Patient education regarding nitroglycerine use
• Reducing tolerance to nitrate therapy
• Initial drug therapy recommendations for patients with angina and alternative agents to use when contraindicated
• Drugs contraindicated in patients with angina
Chapter 36: Heart Failure
• Pathophysiology and classification of heart failure
• Etiology, diagnosis, risk factors and clinical findings
• Differentiate between systolic and diastolic dysfunction and know common causes of each
• Drugs to avoid
• Diagnostic testing
• Treatment and rational drug selection
• Limited role of digoxin in treatment
• Symptoms of digoxin toxicity
• Drugs contraindicate in patients with heart failure
Chapter 39: Hyperlipidemia
• Etiology, diagnosis, risk factors and clinical findings
• Diagnostic testing & monitoring
• Differentiate statins according to strength
• Treatment and rationale drug selection
• Alternative therapies (Omega 3 fatty acids)
• Hyperlipidemia medications associated with improved cardiac outcomes
• Benefits and mechanism of action for non-statin hyperlipidemia medications
• Heart failure treatments according to stage of failure
Chapter 39: Hypertension
• Etiology, diagnosis, risk factors and clinical findings
• Treatment and rationale drug selection
• Antihypertensives contraindicated in pregnancy
• Preferred antihypertensives for blacks
• Contraindications for beta blockers
• Precautions and education for beta blockers
• Antihypertensive step therapy recommendations and monitoring
• JNC 8 hypertension guidelines
• Preferred class for initial drug therapy in hypertension treatment
• Added benefits of beta blocker therapy for hypertension
NR566 Week 4 Study Outline
Many questions are written to assess your clinical application of the material from the textbook, in real-world scenarios.
Chapter 25: Drugs Used in Treating Inflammatory Processes (p. 801-834 only)
• Know the pharmacodynamics, pharmacotherapeutics clinical use, drug interactions and adverse drug reactions for:
o Non-steroidal anti-inflammatory drugs (NSAIDs)
o Aspirin (ASA)
o Gout medications
• Also know:
o Drug of choice for treatment of gout and most common adverse effects
o Role of NSAID use in treatment of gout
o Gout medications that require renal or hepatic dose adjustments
o Allopurinol drug interactions and medications to avoid
o Signs of aspirin toxicity
Week 4 contains the midterm exam which covers content from weeks 1, 2, 3 & 4. Be sure to use the study outlines from weeks 1-3 along with this outline to prepare for the exam.
NR566 Week 5 Study Outline
Many questions are written to assess your clinical application of the material from the textbook, in real-world scenarios.
Chapter 18: Drugs Affecting the Hematopoietic System
• Know the pharmacodynamics, pharmacotherapeutics clinical use, drug interactions and adverse drug reactions for:
o Anticoagulants
• Also know:
o Use of anticoagulants in pregnancy
o Patient instructions for administration of clopidogrel (Plavix) and warfarin (Coumadin)
o Thromboprophylaxis
o Population needed warfarin starting dose adjustment
o INR target goals
o Anticoagulant preferred for patients at high risk for stroke with atrial fibrillation
o Drugs which decrease anticoagulant medication effectiveness
Chapter 19: Drugs Affecting the Immune System
• Know the pharmacodynamics, pharmacotherapeutics clinical use, drug interactions and adverse drug reactions for:
o Immunizations
• Also know:
o Differentiate between the types of vaccines (live, attenuated, etc.)
o Immunization types and recommended administration schedule
o Contraindications for each immunization
o PPD administration
o Post-exposure prophylaxis for rabies
Chapter 27: Anemia
• Differentiate between the types & etiologies of the anemias
• Relevant diagnostic tests
• Prevention & treatment for the anemias
• Monitoring and outcome evaluation
• Recommended amount of iron supplementation for breastfed infants
• Medication to reduce the number of acute sick cell crisis events
• Vitamin deficiency and risk for neural tube defects during pregnancy
• Folate requirements during pregnancy
• Treatment for anemia of chronic disease
• Prevention of pneumococcal sepsis in children with sickle cell anemia
Chapter 37: HIV & Aids
• Know the pharmacodynamics, pharmacotherapeutics clinical use, drug interactions and adverse drug reactions for:
o Antiretroviral medications
• Also know:
o Goals of therapy
o Treatment in special populations (pregnancy, children)
o Pretesting treatment & predictors of success
o Predictors of success
o Phenotype assays
NR566 Week 6 Study Outline
Many questions are written to assess your clinical application of the material from the textbook, in real-world scenarios.
Chapter 22: Drugs Affecting the Reproductive System
• Know the pharmacodynamics, pharmacotherapeutics clinical use, drug interactions and adverse drug reactions for:
o Erectile dysfunction (ED) drugs
o Estrogens and progesterones
o Antiandrogen drugs
• Also know:
o Monitoring of patients in ED drugs
o Androgen production
o Contraindications for estrogen-containing products
o Progesterone antagonists (box 22-3)
Chapter 31: Contraception
• Differentiate between the different forms of contraception, mechanisms of action, and efficacy
• Combined contraceptive medication
• Use of contraceptives in obese women
• BLACK BOX warnings
• Missed medication instructions
• Estrogen dosing recommendations (table 31-3)
Chapter 38: Hormone Replacement Therapy & Osteoporosis
• Etiology, risk factors, diagnosis & clinical findings
• Optimal time frame for hormone replacement therapy
• Hormone replacement therapy in women with a uterus versus without
• Treatment goals and outcome evaluation
• Osteoporosis medication mechanisms of action
• Contraindications for bisphosphonate therapy
• Risks and benefits of hormone replacement therapy
• T-scores and recommended osteoporosis medication
Chapter 44: Sexually Transmitted Infections & Vaginitis
• Etiology, diagnosis, risk factors and clinical findings
• Diagnostic testing, outcome evaluation & recommendations for rescreening
• Treatment guidelines
• Metronidazole educations
NR566 Week 7 & 8 Study Outline
Many questions are written to assess your clinical application of the material from the textbook, in real-world scenarios.
Chapter 48: Women as Patients
• Non-pharmaceutical treatment of symptoms associated with menopause
• Pharmacokinetic gender differences between men and women
• Rationale drug selection for PMDD
• Treatment for primary dysmenorrhea
• Patient education for NSAID administration to treat dysmenorrhea
• Recommended calcium and vitamin D intake for adolescents and adults
• LGBTQ population
Chapter 49: Men as Patients
• Testosterone therapy and monitoring
• Contraindications for testosterone replacement therapy
• Causes of primary and secondary hypogonadism
• Rational drug selection for ED
• Contraindications for PDE-5 inhibitors
• Adverse effects of PDE-5 inhibitors
• Pharmacokinetic gender differences between men and women
• Erythrocytosis from overuse or abuse of testosterone
Chapter 50: Pediatric Patients
• Influences on medication adherence
• Education on medication administration for infants
• Use of topical steroids in young children & infants
• Dosing of acetaminophen and ibuprofen in infants & children
• Pain relief in infants & children
Chapter 51: Geriatric Patients
• Physiologic changes in geriatric patients (effects of aging)
• Pharmacodynamic and pharmacokinetic implications of these changes
• Steps to avoid polypharmacy
• Common herbal medications used by elderly patients
• Hypoglycemia in geriatric patients
Week 8 is the midterm exam which covers content from weeks 5, 6 & 7. There are no readings in week 8. Be sure to use the study outlines from weeks 5 & 6 along with this outline to prepare for the exam. [Show Less]