• Antacids MOA
- Neutralize gastric acid to bring the pH above 3 and inactivate pepsin
• which antacids have the highest absolute neutrophil count
... [Show More] (ANC)?
- sodium bicarbonate and calcium carbonate
• When aminopenicillins are combined with beta-lactamase inhibitors
- their spectrum in broadened
• beta-lactamase inhibitors that can be combined with aminopenicillins
- clavulanate, sulbactam, & tazobactam
• Penicillinase-resistant penicillins drugs
- Nafcillin
- Oxacillin
- Cloxacillin
- Dicloxacillin
- Methicillin
• Penicillinase-resistant penicillins active against
- Streptococcus, MSSA, some coagulase-negative staphylococci, peptostreptococcus
• Anti-pseudomonal penicillin drugs
- Piperacillin
- Ticarcillin
- combination:
o piperacillin/taxobactam
- ticarcillin/clavulanate
• Anti-pseudomonal penicillins active against
- gram (-) organisms
• 1st generation cephalosporins drugs
- Cephradine (Anspor)
- Cefazolin (ancef)
- Cefadroxil (Duricef)
- Cephalexin (keflex)
• What do calcium containing antacids needs for absorption?
- vitamin D
• Antacid Indications
- hyperacidity,
- PUD, GERD, Calcium deficiency, Chronic Renal failure, osteoporosis prevention
• Monitoring after given antiviral for flu
- no flu vaccine for 2 weeks before or 48 hours after antiviral is given
• 1st line therapy for uncomplicated UTI
- trimethoprim/sulfamethoxazole (Bactrim)
• what causes ophthalmia neonatorum
- chlamydia
• patient education for albendazole & mebendazole
- take with a high fat meal
• patient education for ivermectin
- take on empty stomach
• patient education for ibendazole
- don't use if pregnant; use back of contraceptive
• Aminopenicillins Drugs
- Amoxicillin
- Ampicillin
- Combinations:
- Amoxicillin-clavulanate (Augmentin)
• Antifungal (Antimycotics) classes
- azoles
- polyene macrolides
- Allylamines
- Nuclear Acid Synthesis inhibitors
- Griseofulvin
• Azoles - Triazoles drugs
- fluconazole (Diflucan)
- itraconazole (Onmel)
- voriconazole (Vfend)
- Clotrimazole
- Ketoconazole
- minonazole
- terconazole
- tioconazole
• Polyene Macrolides drugs
- amphotericin B
- nystatin
• Allylamines Drugs
- Terbinafine (Lamasil)
- Naftifine
• Nuclear acid synthesis inhibitor drugs
- Flucytosine
• Fluoroquinolone older drugs
- cipofloxacin (cipro)
- norfloxacin (noroxin)
- ofloacin (flovin)
• Fluoroquinolones new drugs
- gemifloxacin (factive)
- levofloxacin (levaquin)
- moxifloxacin (avelox)
• Macrobid indication
- UTI
• the most common cause of Traveler's diarrhea
- E. coli
• PUD stepped-approach algorithm
- Step 1: lifestyle modification/antacids
- Step 2: H. pylori testing/PPI
- Step 3 (uncomplicated): tx for H.pylori
- Step 4 (uncomplicated): PPI continues for 8-12 weeks until healed
- Step 5 (uncomplicated, low risk): no on-going therapy
- Step 5 (uncomplicated, high risk): PPI or H2RA (smokers, >60, CPOD, CAD, hx of bleeding, ulcers or NSAIDs)
- Step 3 (complicated, bleeding): refer to GI for endoscopy
- Step 4 (complicated): tx for H. pylori
- Step 5 (complicated): repeat endoscopy in 12 weeks to determine healing
• what causes most diarrhea?
- infection, food or drug ingestions, or inflammatory bowel disease [Show Less]