NR 507 Week 3 Quiz / NR507 Week 3 Quiz (Latest): Advanced Pathophysiology: Chamberlain College of Nursing
Chamberlain NR 507 Week 3 Quiz / NR507 Week 3
... [Show More] Quiz (Latest): Advanced Pathophysiology
1. Question : The underlying disorder of _____ anemia is defective secretion of intrinsic factor, which is essential for the absorption of vitamin B12.
microcytic
pernicious
hypochromic
hemolytic
Question 2. Question : Clinical manifestations of mild to moderate splenomegaly and hepatomegaly, bronze-colored skin, and cardiac dysrhythmias are indicative of which anemia?
Iron deficiency
Pernicious
Sideroblastic
Aplastic
Question 3. Question : In hemolytic anemia, jaundice occurs only when
erythrocytes are destroyed in the spleen.
heme destruction exceeds the liver’s ability to conjugate and excrete bilirubin.
the patient has elevations in aspartate transaminase (AST) and alanine transaminase (ALT).
the erythrocytes are coated with an immunoglobulin.
Question 4. Question : Which anemia produces small, pale erythrocytes?
Folic acid
Hemolytic
Iron deficiency
Pernicious
Question 5. Question : A woman complains of chronic gastritis, fatigue, weight loss, and tingling in her fingers. Laboratory findings show low hemoglobin and hematocrit levels, and a high mean corpuscular volume. These findings are consistent with _____ anemia.
folate deficiency
pernicious
iron deficiency
aplastic
Question 6. Question : What is the pathophysiologic process of aplastic anemia?
Autoimmune disease against hematopoiesis by activated cytotoxic T cells
Malignancy of the bone marrow in which unregulated proliferation of erythrocytes crowd out other blood cells
Autoimmune disease against hematopoiesis by activated immunoglobulins
Inherited genetic disorder with recessive X-linked transmission
Question 7. Question : Which proinflammatory cytokines are responsible for the development and maintenance of DIC?
Granulocyte colony-stimulating factor (G-CSF); IL-2, IL-4, and IL-10; and IFN-g
Granulocyte-macrophage colony-stimulating factor (GM-CSF); IL-3, IL-5, and IL-9, and IFN-g
Macrophage colony-stimulating factor (M-CSF); IL-7, IL-11, and IL-14; and PAF
TNF-a; IL-1, IL-6, and IL-8; and PAF
Question 8. Question : Heparin-induced thrombocytopenia (HIT) is described as a(n)
IgG immune-mediated adverse drug reaction that reduces circulating platelets.
hematologic reaction to heparin in which the bone marrow is unable to produce sufficient platelets to meet the body’s needs.
IgE-mediated allergic drug reaction that reduces circulating platelets.
cell-mediated drug reaction in which macrophages process the heparin and platelet complexes that are then destroyed by activated cytotoxic T cells.
Question 9. Question : Which of the following is a description consistent with chronic lymphocytic leukemia (CLL)?
There are defects in the ras oncogene, TP53 tumor-suppressor gene, and INK4A, the gene encoding a cell-cycle regulatory protein.
The bone marrow and peripheral blood are characterized by leukocytosis and a predominance of blast cells. As the immature blasts increase, they replace normal myelocytic cells, megakaryocytes, and erythrocytes.
There is failure of B cells to mature into plasma cells that synthesize immunoglobulins.
The translocation of genetic material from genes 9 and 22 creates an abnormal, fused protein identified as BCR-ABL.
Question 10. Question : What is the most common cause of vitamin K deficiency?
Administration of warfarin (Coumadin)
Total parenteral nutrition (TPN) with antibiotic therapy
An IgG-mediated autoimmune disorder
Liver failure
Question 11. Question : Idiopathic thrombocytopenic purpura (ITP) is an autoimmune process involving antibodies against
neutrophils.
eosinophils.
platelets.
basophils.
Question 12. Question : The sickle cell trait differs from sickle cell disease in that the child with sickle cell trait
inherited normal hemoglobin A from one parent and Hb S from the other parent, whereas the child with sickle cell disease has Hb S from both parents.
has a mild form of sickle cell disease that causes sickling during fever and infection, but not during acidosis or hypoxia, whereas the child with sickle cells disease develops sickling during each of these conditions.
has a milder form of the disease that is characterized by vaso-occlusive crises and is believed to result from higher hemoglobin values and viscosity.
has the mildest form of the disease with normal hemoglobin and hemoglobin F, which prevents sickling.
Question 13. Question : In a full-term infant, the normal erythrocyte life span is _____ days, whereas the adult is _____ days.
30 to 50; 80
60 to 80; 120
90 to 110; 140
120 to 130; 150
Question 14. Question : What is the name of the disorder in which levels of bilirubin remain excessively high in the newborn and are deposited in the brain?
Kernicterus
Icterus neonatorum
Jaundice
Icterus gravis neonatorum
Question 15. Question : The type of anemia that occurs as a result of thalassemia is
microcytic, hypochromic.
microcytic, normochromic.
macrocytic, hyperchromic.
macrocytic, normochromic.
Question 16. Question : G6PD and sickle cell disease are
inherited X-linked recessive disorders.
inherited autosomal recessive disorders.
disorders initiated by hypoxemia and acidosis.
diagnosed equally in men and women.
Question 17. Question : An individual who is demonstrating elevated levels of troponin, creatine kinase (CK), and lactic dehydrogenase (LDH) is exhibiting indicators associated with:
myocardial ischemia.
hypertension.
myocardial infarction (MI).
coronary artery disease.
Question 18. Question : Which of the following is manufactured by the liver and primarily contains cholesterol and protein?
Very-low-density lipoproteins (VLDLs)
Low-density lipoproteins (LDLs)
High-density lipoproteins (HDLs)
Triglycerides (TGs)
Question 19. Question : Atherosclerosis causes an aneurysm by
causing ischemia of the intima.
increasing nitric oxide.
eroding the vessel wall.
obstructing the vessel.
Question 20. Question : Cardiac cells can withstand ischemic conditions and still return to a viable state for how many minutes?
10
15
20
25
Question 21. Question : An infant has a loud, harsh, holosystolic murmur and systolic thrill that can be detected at the left lower sternal border that radiates to the neck. These clinical findings are consistent with which congenital heart defect?
Atrial septal defect (ASD)
Ventricular septal defect (VSD)
Patent ductus arteriosus (PDA)
Atrioventricular canal (AVC) defect
Question 22. Question : The foramen ovale is covered by a flap that creates a check valve allowing blood to flow unidirectionally from the _____ to the _____.
right atrium; right ventricle
right ventricle; left ventricle
right atrium; left atrium
left atrium; left ventricle
Question 23. Question : What is the most important clinical manifestation of aortic coarctation in the neonate?
Congestive heart failure (CHF)
Cor pulmonale
Pulmonary hypertension
Cerebral hypertension
Question 24. Question : Which heart defect produces a systolic ejection murmur at the right upper sternal border that transmits to the neck and left lower sternal border with an occasional ejection click?
Coarctation of the aorta
Pulmonic stenosis
Aortic stenosis
Hypoplastic left heart syndrome
Question 25. Question : When does systemic vascular resistance in infants begin to rise?
One month before birth
During the beginning stage of labor
One hour after birth
Once the placenta is removed from circulation [Show Less]