NBME CBSE REAL EXAM/ NBME CBSE 200 QUESTIONS AND ANSWERS/ NBME CBSE LATEST 2023-2024/ Review (Recent Exam)
Chagas Disease ---------- Correct Answer
... [Show More] -------- Caused by Trypanosoma cruzi parasite passed in the feces of Reduviidae/kissing bug
Penetrates broken skin or intact mucous membranes forming a pseudocyst releasing inflammatory infiltrates into myocytes; stains with Giemsa & Wright
Romana sign occurs when portal of entry is the conjunctiva or eyelid
May resulting in:
Enlarged heart- CHF, sudden cardiac arrest
Enlarged esophagus- difficulty swallowing
Enlarged colon- abdominal pain or constipation
Treat with benznidazole or nifurtimox
Monocytes ---------- Correct Answer -------- cell with half-moon shaped nucleus that participates in phagocytosis
Chronic graft rejection ---------- Correct Answer -------- multifactorial but typically involves arteriosclerosis
HLA-B27 ---------- Correct Answer -------- PAIR:
Psoriasis
Ankylosing spondylitis- chronic synovitis destroying cartilage typically in young men
Inflammatory bowel dz- Crohn's & UC
Reactive Arthritis-
Reactive Arthritis ---------- Correct Answer -------- Arthritis as a reaction to a bacterial infection such as Campylobacter, Chlamydia, Salmonella, Shigella, or Ureaplasma.
Associated with conjunctivitis & uveitis
Gaucher (Type 1) ---------- Correct Answer -------- AR Lysosomal storage disease
Accumulation of sphingolipid glucocerebroside
Most common
Wrinkled tissue paper
I Cell disease ---------- Correct Answer -------- Failure of Golgi apparatus to phosphorylate mannose 6-phosphate the marker to export enzymes to lysosomes resulting in accumulation of lysosomal enzymes in serum
Nitroblue tetrazolium test ---------- Correct Answer -------- Aqualitative test to determine defects in NADPH oxidase
Negative: CGD
Positive: Acute Hepatitis, Mono
CGD (chronic granulomatous disease) ---------- Correct Answer -------- inability to produce NADPH oxidase; susceptible to Cat + organisms; elevated neutrophils w/ normal T cell
Gp91 phox subunit: heme binding subunit of superoxide generating NADPH
Treat with interferon gamma
Clarithromycin (macrolide) ---------- Correct Answer -------- ADR of metallic taste & GI
Codeine ---------- Correct Answer -------- ADR resp. depression, euphoria, & constipation
Cyclobenzaprine ---------- Correct Answer -------- Structurally similar to TCAs w/ anticholinergic side effects used for relief of muscle spasms
May exacerbate glaucoma
Naproxen ---------- Correct Answer -------- ADR of GI & renal (in elderly)
Timolol ---------- Correct Answer -------- Used in HTN & glaucoma; ADR of bradycardia & worsening asthma
Bacterial vaginosis ---------- Correct Answer -------- Sloughed mucosal cells = clue cells
Trichomoniasis ---------- Correct Answer -------- Cilated, motile trophozoites w/ corkscrew-like motility
Autism ---------- Correct Answer -------- Lack of eye contact, verbal communication, & separation anxiety; repetitious behavior
Emphysema ---------- Correct Answer -------- Decreased FEV1/FVC ratio, normal FVC; TLC, FRC, & RV increase
Parathyroid hormone(PTH) vs phosphate in hypercalcemia ---------- Correct Answer -------- PTH: rapid & direct
Phosphate: slow & indirect [Show Less]