NAPSR FINAL EXAM ANSWERS (Spring 2020) Revised, Attempt score: 160 Out of 160 points 1. : How are drugs sorted into therapeutic groups and classes? A.
... [Show More] first by the conditions that they are used to treat. and then by their mechanisms of action 2. : Bone marrow transplants...are a type of stem cell therapy. unless patient's own cells are reinjected. 3. : What does AMA stand for. American Medical Association 4. : What section of a drug's package insert describes situations in which the drug should not be used because the risks outweigh the therapeutic benefits. Contraindications 5. : What is tertiary care? Highly specialized medical and surgical care provided by a large medical center for unusual or complex medical problems brand quality 6. : What are vasodilators used to do? Decrease vascular resistance and increase blood flow 7. : What is the name of the condition that occurs after a specific dose of a drug is given at such regular intervals that absorption and elimination (and therefore drug plasma concentration) have become fairly constant? Steady state 8. : Which statement is TRUE about ocular administration? Ocular administration is used primarily to treat the eye. 9. : Which entities invest's the most money in pharmaceutical R&D?U.S. pharmaceutical companies 10. : How are most drugs excreted?Via the kidneys 11. : Over the last few decades, what has happened to legal limitations on sales' reps discussions about of label uses?Limitations have decreased. 12. : According to your manual, which of the following is an example of a branding"fundamental"?The brand name 13. : What does it mean if two drugs are "at parity"?Both drugs are essentially in a neutral position 14. : Who is most likely to benefit from electronic sampling programs?Everyone would benefit equally from electronic sampling programs 15. : When referring to medication dosage, which abbreviation means "one-half'SS 16. : What is an internist?a physician who practices internal medicine 17. : Which of the following is a type of white blood cell?Lymphocytes lOMoARcPSD|11518826 Downloaded by sammie kihiko ([email protected]) 18. : Why are novice sales representatives often placed in charge of negotiating MCO formularies?They are not. This job is usually reserved for more experienced reps. 19. : What proportion of the drugs tested on human subjects are eventually approved by the FDA?about 70% 20. : According to a study discussed in your manual, how do most physicians prefer to receive their drug samples?directly from sales representatives 21. : Which of the following is an example of a central value?l buy Advil to show that l'm a modern consumer. 22. : Which of the following specialties likely has the MOST emergency calls?cardiology 23. : What afects the rate of active transport?the availability of carriers and energy 24. : Over the last few decades, what has happened to the FDA approval time for new drugs?lt has been shortened to reduce the cost of new drug development. 25. : Which of the following would NOT help improve compliance?pharmacists understanding how generics differ from brand name drugs 26. : Which entity chooses a drug's trade name?the FDA 27. : What type of stem cells are obtained from embryos and can develop into any cell type?totipotent. 28. : As the price a patient pays for a prescription increases, what happens to the likelihood that the patient will fill it?lt remains unaffected because the prescription is needed. 29. : Most involuntary movements come from which type of muscle tissue?cardiac and smooth 30. : Which of the following is NOT one of the body's major organ systems?the cellular system 31. : How do most drugs exert their primary physiological efects?by binding to cell receptors that are sensitive to their presence 32. : What is the most reliable source of information for determining therapeutically equivalent drug products?Orange Book 33. : What does subcutaneous mean?beneath the outer skin 34. : What should a sales representative do if all of the prime spaces in a drug cabinet are occupied?ask staff for permission to move some of the other products in the cabinet 35. : Which one of the following testing methods is not commonly used for Allergy Testing?Urine test 36. : The FDA defines API as the active ingredient in a drug, which produces the desired change in the body.pharmaceutical 37. : What are the 2 legal classifications of wholesalers?primary and secondary wholesale distributors 38. : What term describes the usage of a medication for purposes other than the FDA- approved indications on the labeling?off−label usage 39. : What is the acronym for pharmacokinetics?PK 40. : Which of the following is not a purpose of the Arthrocentesis diagnostic test?To monitor joint density 41. : What is typically NOT a characteristic of a pharmaceutical sales rep?Pharmaceutical sales reps are not concerned about competitors. 42. : What entity grants drug patents? the U.S. Patent and Trademark Office 43. : Which of the following refers to all active and inert pharmaceutical ingredients in a drug, including fillers and colors? formulation 44. : What is the diference between potency and efficacy?Potency refers to the drug's strength, while efficacy refers to its effectiveness. 45. : The neurological examination is a series of simple questions and tests that provide crucial information about nervous system. It is an inexpensive, non-invasive way to determine what might go wrong. The neurological examination is devided into several components. Which of the below is not one of them?Heart rate 46. : How many names must a drug have?at least three 47. : How has a longer development time increased the cost of bringing a new drug to market? by increasing the cost of capital 48. : 50. Senior citizens consume over times as many pharmaceuticals as people under 65.three times 49. : 51. What agency regulates the distribution and use of narcotics?DEA 50. : 52. What is passive difusion?the use of energy to help a substance pass from a low concentration gradient to a high one 51. : 53. What are the MAIN categories of drugs under FDA jurisdiction?prescription and non prescription 52. : 54. Which of the following is a natural uterotonic agent? oxytocin 53.: 55. What are all metabolites?products of metabolism 54.: 56. When a drug is administered orally, where does first-pass metabolism occur?liver 55.: 57. What is the medical term for swelling?edema 56. : 58. Which of the following is NOT part of the Seven Step Cascade of Emotion?be a consultant. not a rep 57. : 59. Which part of a clinical research paper is frequently referred to as the road map? abstract 58.: 60. Which of the following is a main active ingredient in lung surfactants? theophylline 59.: 61. What does parenteral mean?injection 60. : 62. Which term denotes a type of substance that enhances the action of a drug or antigen?adjuvant 61. : 63. If a sales representative's product is placed on the second tier of a standard three-tier formulary, which of the following is most likely true?lt probably has exclusive preferred status if it is not at parity with any other drugs. 62.: 64. Which of the following is NOT one of the four basic transport mechanisms?homeostasis 63. : 65. Which statement accurately describes a relationship between drug agonists and antagonists?Agonists and antagonists can be used together. 64. : 66. What is the study of the efects and movement of drugs in the human body? clinical pharmacology 65. : 67. According to your manual, what is a common complaint that physicians have about traditional sampling methods?that drug sample supply is too unpredictable 66. : 68. Which of these entities is formed by two or more hospitals or other healthcare entities to negotiate reduced rates with its aggregated purchasing power?GPO 67.: 69. What is another name for a drug derived from a biologic compound?large molecule 68. : 70. What is the most common policy regarding pharmaceutical reps dispensing drug samples in hospitals?Drug sampling is often forbidden. 69. : 71. Which of the following would help you build trust with a physician?asking if he or she is having any problems with the managed care coverage of your products 70. : 72. What term denotes the diference between the usual efective dose and the dose that induces severe or life-threatening side efects?margin of safety 71. : 73. What are excipients?the inert ingredients in a drug formulation 72.: 74. What is another term for the AWP?list price 73.: 75. Which of these is the most likely use for a uterotonic agent?to induce labor 74. : 76. Ordinary x-rays are the most common imaging test as these provide a picture of the inside of the body. Which of following is not a common medical imaging test?Positron Emission Tomography (PET) 75. : 77. Why are oral drugs often taken on an empty stomach?to pass through the stomach more quickly 76. : 78. What is one factor that diferentiates community health centers from hospitalsCommunity health center formularies are more restrictive. 77. : 79. How does drug sampling provide a social benefit?Doctors often use drug samples to treat patients who otherwise could not afford it 78. : 80. Which medical term denotes the use of a stethoscope to listen to the heart? auscultation 79.: 81. What do enteric coatings do?prevent dissolution in the stomach 80.: 82. What is the duration of exclusivity for orphan drugs?7 years 81.: 83. What do National Account Managers do?negotiate contracts with MCOs and PBMs 82. : 84. What does it usually mean if a drug recall is voluntary?The manufacturer has recalled the product on its own. but negotiated with the FDA beforhand 83.: 85. Which phase of clinical trials is also known as the pivotal phase?phase lll 84. : 86. During which phase of clinical trials is the new drug's safety and efectiveness first tested in the target group?phase ll 85.: 87. How do antacids work?by raising gastric pH 86.: 88. What is one of the biggest time wasters for a pharmaceutical sales rep?travel time 87. : 89. What happens when equilibrium is reached?equal numbers of molecules cross the membrane in both directions 88.: 90. What are the most common vectors used in gene therapy?viruses 89.: 91. What is the percentage fee that the dispenser pays the wholesaler for distribution?upcharge 90. : 92. What is the diference between a chronic (or continuing) reaction, and a delayed reaction? chronic eractions persist for a ling time wheras delayed reactions take some time to develop 91.: 93 What is clinical efect?the response produced by a medication 92. : 94. Which of the following is an example of noncompliance?a patient forgetting to take a drug at a specified time of day 93.: 95. What is the average circulation time of blood?about a minute 94. : 96. What is one way in which pharmaceutical selling is diferent from selling in most other industries?Representatives do NOT sell to the end user of the product. 95. : 97. From what types of entities do primary wholesale distributors buy most of their drugs?manufacturers 96. : 98.What is the Office of the Inspector General (01G)?an arm of the Department of Health and Human Service 97. : 99. What are doctors required to consider when deciding whether or not to prescribe a particular drug?the severity of the disorder being treated and the effect it has on the patient's quality of life 98. : 100. Which entity assigns a new drug its generic names?the United States Adopted Name Council 99.: 101. Drugs can be used days beyond their expiration date.D. none of these 100. : 102. What is necessary for a drug to be excreted extensively via the kidneys?A. The drug must be water−soluble. and not bind too tightly to proteins in the bloodstream. 101. : 103. Which organization or individual initiates the clinical trial and finances the study?D. sponsor 102.: 104. The _ name describes the atomic or molecular structure of a drug.A. chemical 103. : 105. Under PhRMA Code, is it acceptable or unacceptable for a pharmaceutical sales rep to take a physician and the physician's spouse to a fundraising dinnerD. unacceptable 104. : 106. The Hatch-Waxman Act is considered the most significant drug-related afecting the pharmaceutical industry since 1962.legislation 105. : 107. What term denotes the the extent, quality, or degree to which a substance is poisonous or harmful to the body?toxicity 106. : 108. What issue has MOST encouraged consumers' desire to see more OTC medications?B. lack of insurance coverage 107. : 109. What is the degree to which a medication produces a therapeutic efectB. efficacy 108.: 110. What is the most important benefit of electronic prescribing?D. safety 109. : 111. When does the FDA regulate generic drugs?C. always 110. : 112. Which phase of trials largely determines the clinical dose?B. Phase ll trials 111. : 113. What is an advantage of inactivated vaccines over attenuated vaccinesC. lnactivated vaccines have a more stable shelf life. [Show Less]