1. Pharmaceuticals are arguably the most so- cially important healthcare product. (T/F) 2. Pharmaceutical development is a high-risk undertaking, in which
... [Show More] many promising leads prove disappointing. (T/F) 3. Pharmaceutical sales are highest in which geographical regions? 4. The U.S. accounts for about of the world's pharmaceutical revenues. 5. Which of the following has fueled recent growth in the pharmaceutical industry? 6. According to the manual, which statement accurately describes the predicted relation- ship between pharmaceutical companies and genomic research facilities? 7. Prescription drug therapy is not cost-effec- tive for insurance companies and healthcare providers. (T/F) 8. The high price of healthcare is explained by the high price of medicines. (T/F) 9. One of the oldest and least effective phar- maceutical marketing techniques is DTC (di- rect-to-consumer) advertising. (T/F) 10. What influences the number of districts in a region? 11. What is an example of the regionalization of healthcare delivery systems? true true The U.S., Western Europe, and Japan 50% population growth and in- creased life expectancies Partnerships between phar- maceutical companies and genomic companies will not prove immediately prof- itable false false false the region's population California and Florida have different prescription reim- bursement policies 12. The heart of a pharmaceutical sales team is the regional manager. (T/F) 13. Most DMs did not start as representatives. (T/F) false false 14. How many territories are in a typical district? 8 to 12 15. What is the most effective method for grab- bing market share? 16. Pharmaceutical reps mainly visit pharma- cies. (T/F) 17. It usually only takes 1-2 calls to a physician before he or she commits to prescribing your product. (T/F) 18. The pharmacist may dispense a product oth- er than what the physician prescribed. (T/F) 19. According to ch. 12 of the manual, which of the following would classify as "payers"? 20. According to the manual, what defines "eth- ical pharmaceutical companies"? 21. One of the most disappointing results of the pharmaceutical industry's continued invest- ment in R & D is the few new drugs being approved and in development. (T/F) 22. Thanks to modern medicines, how long are people newly diagnosed with HIV expected to live? 23. How much has the average American lifes- pan increased since 1890? 24. What is a treatment group? comparative selling false false true employers researching and developing novel drugs false another 50 years almost 30 years 25. What is the main difference between a blind- ed and double-blinded study? a group of patients as- signed to receive a specific treatment in a double blinded study, neither the study staff nor the study participants know which subjects are in the ex- perimental group and which are in the control 26. What does "asymptomatic" mean? not exhibiting signs or symptoms 27. Which term denotes the study of bodily func- tions (as opposed to structures)? 28. In its broadest definition, a drug is any sub- stance that produces a physical or psycho- logical change in the body. (T/F) 29. How does the Federal Food, Drug, and Cos- metic Act (FFDCA) define a drug? physiology true any substance intended for use in the diagnosis, cure, mitigation, treatment or pre- vention of disease, or a sub- stance other than food in- tended to affect the struc- ture or function of the body 30. Which statement about vitamins is correct? most of the body's required vitamins must be taken from outside the body 31. ADME testing measures the rate at which the body absorbs the drug, distributes it to the organs necessary to produce the desired effect, metabolites it into waste material and then excretes it from the body. true 32. ADME testing is primarily used in what field? pharmacokinetics 33. Which statement about placebos is correct? placebo effects can lead to withdrawal symptoms 34. On average, only about 5 of 4,000 drugs stud- true ied in the lab are eventually studied in peo- ple. (T/F) 35. Which statement is true about drugs taken sublingually? 36. What are 3 of the 7 rights of drug administra- tion? 37. Pro-drugs are administered in an active form, which is metabolized into an inactive form. (T/F) sublingual drugs are ab- sorbed directly and almost immediately into the blood- stream the right patient, the right drug, and the right dose false 38. The kidney of an 85-year-old person excretes around 50% drugs only as efficiently as that of a 35-year-old person. 39. The normal age-related decrease in kidney function can help doctors determine an ap- propriate dosage based solely on a person's age. (T/F) true 40. What differentiates a caplet from a tablet? caplets are shaped like cap- sules and have film coat- ings to aid in swallowing 41. Where will you find the legend "Caution: Fed- eral Law prohibits dispensing without a pre- scription"? on the label of all prescrip- tion drugs 42. What happens in slow acetylators? Drugs that are metabo- lized by N-acetyl trans- ferase tend to reach higher blood levels and remain in the body longer 43. About of the people in the U.S. are "slow 50% acetylators" 44. Which of the following statements about drug-drug interactions is INCORRECT? 45. Smoking decreases the effectiveness of some drugs. 46. Which of the following statements about di- etary supplements is INCORRECT? 47. Which statements is/are INCORRECT about an ideal drug, or "magic bullet" as Ehrlich phrased it? 48. Which statement accurately differentiates resistance from tolerance? 49. Between 3% and 7% of hospital admissions in the US are estimated to be for treatment of adverse drug reactions. (T/F) 50. Which statement is true about the universal scale for quantifying the severity of an ad- verse drug reaction? Drug-drug interactions are always harmful true Because dietary supple- ments are not drugs, inter- actions with drugs are not a concern All are correct - it does not exist - it would be aimed precisely at a disease site - it would not harm healthy tissues tolerance refers to a per- son's diminished response to a drug after repeated use, while resistance ap- plies to microorganisms' or "cancel" cells' abilities to withstand drug effects true none of these statements are true because there is no such scale - the severities of adverse 51. Why is noncompliance a serious public health concern? 52. Which of the following is NOT eligible for patent protection under US regulations? 53. Drugs' trade names are often unrelated to their intended use. (T/F) 54. Like foods and household products, gener- ic drugs are usually lower quality than the brand name drugs for which they are market- ed as equivalents. (T/F) 55. Legally, bioequivalence of different versions of a drug can vary up to 56. Which of the following statements about bi- ologics is INCORRECT? 57. "Large molecule" products are developed and manufactured by a chemical process. 58. What are drugs that attract or bind to cells receptors in order to mimic or enhance activ- ities by endogenous chemical messengers? drug reactions are quanti- fied by their chronicity - the severities of adverse drug reactions are quanti- fied by their threat to life it increases the cost of med- ical care companies can be grant- ed patents for all of these things - the drug itself - the method of delivering and releasing the drug into the bloodstream - the way the drug is made true false 20% they do not cause immune responses false agonists 59. mechanism of action Which term denotes how an API works in the body? 60. What cements the active and inert compo- nents together to maintain cohesive por- tions? 61. What does the medical abbreviation "BID" denote? 62. What is the medical abbreviation for "as needed"? 63. What components might cause patients' dif- ferent reactions to brand name and generic drugs? binders twice a day PRN [Show Less]