How do antigout medications work? Correct Answer- by inhibiting the infiltration and phagocytosis of
leukocytes, thus decreasing the breakdown of uric
... [Show More] acid to urate crystals.
Deposition of urate crystals causes Correct Answer- pain and inflammation
What is Colchicine Correct Answer- anti-gout medication
how does Colchicine work? Correct Answer- Works by inhibiting inflammation, reducing pain and
swelling
common side effects of Colchicine Correct Answer- GI problems (diarrhea) use with caution in elderly
Also can cause blood dyscrasias & abdominal pain
patient education with Colchicine Correct Answer- Can be given with food & milk to decrease GI issues
Avoid beer, ale, & wine: may cause gout attack
Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
Low dose of Colchicine Correct Answer- Low dose colchicine is 1.2mg followed by 0.6mg one hour later
or 1.8 milligrams total
High dose of Colchicine Correct Answer- high dose colchicine is 1.2mg followed by 0.6mg every four to
six hours; or 4.8mg total.
Difference between high dose and low dose Colchicine Correct Answer- The difference between the two
is low dose is as effective as high dose with a lower side effect profile.
Lab values to monitor with Colchicine Correct Answer- Check renal function test, BUN, Creatine
Patient education with Colchicine Correct Answer- Almost always causes some degree of diarrhea, make
sure patients are aware of this side effect
Patient education with Febuxostat (Uloric) Correct Answer- Gout may worsen with therapy initially
Dietary changes to decrease gout attacks and uric acid deposits. Correct Answer- Avoid beer, ale, & wine
Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
WHO 3 step ladder for pain medication Correct AnswerWhat is not a first line for pain medication? Correct Answer- Narcotics
Recommendations for pain treatment Correct Answer- You want to start with NSAIDs first and then
work your way up from there.
types of Corticosteroid treatment Correct Answer- Prednisone, Cortisone, Dexamethasone
how do Corticosteroids work? Correct Answer- Suppress the inflammatory & immune systems by
inhibiting the synthesis of chemical mediators. [Show Less]