HBO is the therapeutic use of oxygen at pressures greater than ____.
1 atm
HBO is expressed in multiples of atmospheric pressure
... [Show More] ___.
absolute
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1 Atmospheric pressure absolute (ATA)
760 mmHg
Most HBO therapy is conducted at pressures between what?
2-3 ATA
What are the 4 physiologic effects of HBO?
1)Bubble reduction (Boyle's law)
2)Hyperoxygenation of blood and tissue (Henry's law)
3)Vasoconstriction
4)Enhanced host immune function
5)Neovascularization
What is Boyle's law?
P1 V1=P2 V2
Bubble reduction
What is the bends?
decompression sickness where the air is composed for nitrogen and oxygen trapped in the blood or tissues. The bubbles can block blood vessels in many organs. Causes severe pain.
What pressure would a patient with decompression sickness need to be treated with?
6 ATA
How does Boyle's law help with decompression sickness (the bends)?
high pressure decreases the size of these bubbles and minimizes potential harm.
What is Henry's Law?
V= a x Pgas
Hyperoxygenation of blood and tissue
How does Henry's law help with HBO?
Predicts how much of a given gas will dissolve in a liquid. Increasing tissue O2 helps restore WBC function, antimicrobial activity. (why it helps with burns)
Normally only ___ml/dl of O2 dissolves in the plasma. At 3 ATA plasma contains ___ml/dl.
0.3; 7
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How does vasoconstriction help HBO therapy be effective?
hyperoxia affects the cardiovascular system by decreasing the cardiac output which in turn reduces edema and tissue swelling while maintaining tissue oxygenation. (helpful with burns, cerebral edema, and crush injuries)
What is Neovascularization and how does it make HBO effective?
Formation of new capillary beds which aids in tissue repair (why it helps with burns)
What are the 2 methods of HBO therapy?
multiplace chamber
monoplace chamber
Why use HBO therapy?
decompression sickness
air/gas embolism
CO poisoning
Cyanide poisoning
Acute traumatic injury
intracranial abscesses
crush injuries
clostridial gangrene
necrotizing soft-tissue infection
skin graft or flap
diabetic wounds
refractory osteomyelitis
actinomysosis
radiation necrosis
When using HBO for CO poisoning what becomes the half-life of CO? What was it on just 100% O2?
23 minutes; 80 minutes
What are the 3 complication and hazards of HBO therapy?
1)Barotrauma (ears popping)
2)Oxygen toxicity
3)fire, claustrophobia, decreased cardiac output [Show Less]