Final Exam: NR566/ NR 566 (NEW 2024/
2025 Update) Advanced Pharmacology for
Care of the Family Exam Review| Questions
and Verified Answers| 100%
... [Show More] Correct |Grade
A – Chamberlain
QUESTION
When is androgen therapy appropriate vs. not needed related to puberty?
Answer:
in some boys, puberty fails to occur at the usual age (before 15 years old). Most often, this
failure reflects a familial pattern of delayed puberty & does not indicate pathology.
Puberty can be expected to occur spontaneously but later than usual. Hence treatment is not an
absolute necessity. However, some providers will prescribe a limited course of androgen therapy
off label is the psychologic pressure of delayed sexual maturation are causing a boy significant
distress.
In these cases, a limited course of androgen therapy is indicted. Both fluoxymesterone (Androxy,
Halotestin) & methyltestosteone (Methitest) are approved for this purpose. If delayed puberty is
the result of true hypogonadism, long-term replacement therapy is indicated.
QUESTION
Common side effects of androgen therapy
Answer:
Hot flashes, bone fractures, decreased libido, insulin resistance, erectile dysfunction,
gynecomastia, acne, HTN, sterility, hepatotoxicity, mood swings/ aggression.
tell female patients about virilization (deepening of the voice, acne, changes in body & facial
hair, male pattern baldness, menstrual irregularities, increased libido, clitoral enlargement).
Masculinization can occur if taken by children (e.g., sports performance enhancement). Boys
may experience growth of pubic hair, penile enlargement, increased frequency of erections, and
even priapism (persistent erection).
If the patient can become pregnant, emphasize the need for consistent use of reliable
contraception. Hypercholesterolemia, thromboembolic disorders with increased risk of MI,
stroke, DVT, and PE.
QUESTION
Alprostadil is a nonoral drug for erectile dysfunction (ED)
Answer:
that can be given either by injection into the penis or by insertion into the urethra. Because of
this inconvenient method of dosing, this drug is a second-line agent for ED.
QUESTION
Alprostadil is a nonoral drug for erectile dysfunction (ED)
Benefits of various routes
Answer:
Transurethral: Alprostadil pellets (Muse) the only ED drug that is approved for twice-daily use,
is inserted into the urethra. Erection develops 5 to 10 minutes after insertion and lasts 30-60
minutes.
The objective is to employ the smallest dose required to produce an erection sufficient for
intercourse.
Intracavernous:Alprostadil (Caverjet, Caverjet Impulse, Edex) is also available in a form for
direct injection into the corpous cavernosum. The response is rapid and relatively painless.
The objective is sufficient to produce erection but does not last more than 1 hour. Do Not use
more than once in 24 hours.
QUESTION
Contraception
How does carbamazepine impact oral contraceptives and what symptoms may be associated with
that?
Answer:
Carbamazepine is a CYP450 INDUCER and thereby REDUCES oral contraceptive effects.
Women taking OCs in combination with inducers including carbamazepine, phenytoin,
rifampin, alcohol, and sulfonylureas should be alert for indications of reduced blood leve [Show Less]