Common Nursing Medication Review IV / IM / SC complete 2024 update.
Cefazolin (Ancef) - Class Cephalosporin (First Generation)
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Cefazolin (Ancef) - Indication Infection such as :
- Skin infections (including burn wounds)
- Pneumonia
- UTI
- Bone and Joint Infection
- Septicemia
Cefazolin: Pre Operative Prophylaxis, biliary tract infection genital infection, bacterial endocarditis prophylaxis
Cefazolin (Ancef) - Action Binds to bacterial cell wall membrane causing cell death
Cefazolin (Ancef) - 1/2 Life 90-150 min
Cefazolin (Ancef) - Onset / Peak / Duration (IV) IV: Rapid (Onset) | 5 min (Peak) | 6-12 hr (Duration)
Cefazolin (Ancef) - Contraindications - Hypersensitivity to cephalosporins
- Hypersensitivity to penicillins
Cefazolin (Ancef) - Adverse Effects GI: Clostridioides Difficile Associated Diarrhea (CDAD)
Derm: Stevens-Johnsons Snydrome
Neuro: Seizures (High doses)
Misc: Anaphylaxis, Serum sickness
Cefazolin (Ancef) - Assessment - Assess for infection (VS, appearance of wounds, sputum, urine, and stool; WBC)
- Perform history check of any Rx. to penicillin or cephalosporins
- Observe for S/S of anaphylaxis (rash, pruritus, laryngeal edema, wheezing). Keep epinephrine, antihistamine, resuscitation equipment close in case.
- Monitor bowel function. Diarrhea, abdominal cramping, fever, and blood stools should be reported promptly as sign of CDAD (c. diff associated diarrhea)
- Discontinue cephalosporin at first sign of rash; may be life threatening (stevens-johnson syndrome)
Cefazolin (Ancef) - Patient/Family Teaching Instruct patient to notify health care professional if rash or fever and diarrhea develop
Cefazolin (Ancef) - Evaluation/Desired Outcome - Resolution of S/S of infection
- Decreased incidence of infection when used as prophylaxis
Dimenhydrinate (Gravol) - Class Antihistamine
Dimenhydrinate (Gravol) - Indication - Allergic Rx
- Motion sickness
Dimenhydrinate (Gravol) - Action Competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract; blocks chemoreceptor trigger zone, diminishes vestibular stimulation, and depresses labyrinthine function through its central anticholinergic activity (which reduces severity of nausea)
Dimenhydrinate (Gravol) - Contraindications - Hypersensitivity
- angle-closure glaucoma
- Premature or newborn infants
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