CHEMISTRY 241
Fundamentals of Organic
Chemistry Laboratory
Pre-Lab and Post-Lab Reports
2019-2020 Academic Year
Dr. Lawrence Goldman
Professor Tomi
... [Show More] Sasaki
Department of Chemistry
University of Washington
Chemistry 241 2019-2020
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TABLE OF CONTENTS
Check-In Worksheet ................................................................................................................................... 4
Prelab Checklist ...................................................................................................................................... 4
Lab 1: Acid-Base Extraction, Crystallization, and Melting Point .............................................................. 5
Prelab 1 & Checklist............................................................................................................................... 5
Prelab 2 & Checklist............................................................................................................................... 7
Post-Lab Report ...................................................................................................................................... 9
Lab 2: Distillation, Gas Chromatography, and NMR Spectroscopy ........................................................ 12
Prelab & Checklist................................................................................................................................ 12
TLC Analysis Practice (Carried out on GC day).................................................................................. 14
Post-Lab Report .................................................................................................................................... 15
Computational Exercises (submitted with postlab) .............................................................................. 17
Lab 3: Friedel-Crafts Acylation and Column Chromatography ............................................................... 19
Prelab Checklist .................................................................................................................................... 19
Post-Lab Report .................................................................................................................................... 21
Computational Exercises (submitted with postlab) .............................................................................. 24
Lab 4: Relative Reactivities of Aromatic Compounds............................................................................. 29
Prelab Checklist .................................................................................................................................... 29
Post-Lab Report .................................................................................................................................... 30
Computational Exercises (submitted with postlab) .............................................................................. 33
Discussion Day 1: Friedel-Crafts Acylation + Aromatic Bromination .................................................... 37
Lab 5: Stereochemistry of Bromine Addition to Alkenes ........................................................................ 38
Prelab Checklist .................................................................................................................................... 38
Post-Lab Report .................................................................................................................................... 40
Computational Exercises (submitted with postlab) .............................................................................. 42
Lab 6: Grignard Reaction.......................................................................................................................... 44
Prelab Checklist .................................................................................................................................... 44
Post-Lab Report .................................................................................................................................... 46
Computational Exercises (submitted with postlab) .............................................................................. 47
Lab 7: Elimination and Substitution of Alkyl Halides.............................................................................. 49
Prelab Checklist .................................................................................................................................... 49
Post-Lab Report .................................................................................................................................... 50
Computational Exercises (submitted with postlab) .............................................................................. 52
Spectroscopy Worksheet........................................................................................................................... 53
Lab 8: Green Alcohol Oxidation............................................................................................................... 54
Prelab Checklist .................................................................................................................................... 54
Post-Lab Report .................................................................................................................................... 56
Chemistry 241 2019-2020
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Lab 9: Azo Dyes ....................................................................................................................................... 58
Prelab & Checklist................................................................................................................................ 58
Lab Report: Azo Dyes .............................................................................................................................. 59
Report sheet for Spectroscopy Exercise (Due the same day) ............................................................... 61
Discussion Day 2: E2 Elimination + Grignard ......................................................................................... 62 [Show Less]