Chapter10:DrugTherapyforMentalHealth
Visovsky:IntroductiontoClinicalPharmacology,9thEdition
MULTIPLECHOICE
1.
... [Show More] Whichdrugcategoryisusefulinpromotingsleepamongpatientswithinsomnia?
a. Sedatives
b. ACEinhibitors
c. Atypicalantipsychotics
d. Selectiveserotoninreuptakeinhibitors
ANS: A
Sedativesaredrugsthathavethemainpurposeofpromotingsleepbychangingsignalsinthecentraln
ervoussystemandreducingresponsestostimulation.
DIF: CognitiveLevel:Knowing REF: p.184
2.
YouarepreparingtogivethebenzodiazepineValiumtoapatientasapremedicationbeforesurgery.T
hepatientasksyouhowthisdrugworks.Whatisyourbestresponse?
a. “ThisdrugworksbybindingtoreceptorsactingwithGABAtoinducesleep.”
b. “Thisdrugisactsbypreventingbindingtothebenzodiazepinereceptors.”
c. “ThisdrugactsbyinhibitingGABAresponsestorelaxmuscles.”
d. “Thisdrugactsbybindingtoopioidreceptors.”
ANS: A
BenzodiazepinesaresedatinghypnoticdrugsthatdepresstheCNSbybindingtobenzodiazepine(B
NZ)receptorsthatactwithgammaaminobutyricacid(GABA)receptorstoenhanceGABAeffects,resultingsleepandmusclerelaxati
on.
DIF: CognitiveLevel:Applying REF: p.186
3.
Youarecaringforapatientintheclinicsettingwhohasbeentakingabenzodiazepinealprazolam(Xan
ax)foranxiety.Whatpotentialproblemshouldyouobservethispatientfor?
a. Seizureactivity
b. Addiction
c. Insomnia
d. Anorexia
ANS: B
Thebenzodiazepineshaveahigherriskforaddictionanddependencythandothenonbenzodiazepin
es.Theyalsocarryablackboxwarningforcentralnervoussystemdepression.Overdosesarepossibl
eandserious.
DIF: CognitiveLevel:Understanding REF: p.185
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4.
Whichdrugwouldyouanticipatewillbegiventoapatientwhoexperiencedanoverdoseofabenzodia
zepine?
a. Rifampin
b. Naloxone
c. Flumazenil
d. Epinepherine
ANS: C
Thedrugflumazenil(Romazicon)isabenzodiazepinereceptorantagonistandisanantidoteusedtor
everseanoverdoseofeitherabenzodiazepinesedativeoranonbenzodiazepinesedative.Foradults,i
tisgivenintravenouslywithaninitialdoseof0.2mg.Ifthereisnoresponseafter45seconds,thedosec
anberepeated.Afterthat,itcanberepeatedeveryminuteforatotalof4doses.
DIF: CognitiveLevel:Knowing REF: p.187
5. Forwhichpatientwouldbenzodiazepinesbecontraindicated?
a. Afemalewithbreastcancer.
b. Awomanwhois20weekspregnant.
c. Amal [Show Less]