. Which process replaces new bone cells within bone to keep the bone dense?
a. Osteoporosis
b. Osteoblastic activity
c. Osteoclastic activity
d. Bone
... [Show More] resorption of calcium
ANS: B
Osteoblastic activity is the replacement of new bone cells within an existing bone.
Osteoclastic activity removes bone cells. Osteoporosis is the imbalance between osteoblastic
activity and osteoclastic activity that results in decreased bone density. Bone resorption of
calcium is the REMOVAL of calcium from bone storage sites, resulting in bone density loss.
DIF: Cognitive Level: Remembering REF: p. 470
2. Which drug used to treat osteoporosis is available only by subcutaneous injection?
a. Alendronate (Fosamax)
b. Raloxifene (Evista)
c. Ibandronate (Boniva)
d. Denosumab (Prolia)
ANS: D
Denosumab is administered by subcutaneous injection once every 6 months. Alendronate and
raloxifene are oral drugs. Ibandronate may be administered orally or intravenously but not
subcutaneously.
DIF: Cognitive Level: Remembering REF: pp. 472-473
3. In what way do uric acid synthesis inhibitors reduce gout symptoms?
a. Increasing the amount of enzymes that enhance urinary excretion of uric acid
b. Suppressing the reabsorption of sodium and calcium by the kidney tubules
c. Decreasing the inflammation and pain caused by joint damage
d. Suppressing the conversion of purines into uric acid crystals
ANS: D
Most gout is cause by a metabolic problem in which the individual is not able to excrete uric
acid at the same rate it is produced. Rasburicase works by breaking down uric acids so they
can be eliminated. Uric acid synthesis work by reducing the amount of uric acid produced.
They do not enhance urinary excretion or directly interfere with the process of inflammation.
Additionally, they do not affect sodium or calcium reabsorption.
DIF: Cognitive Level: Remembering REF: p. 474
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