CHAPTER 2 Pharmacologic Principles
Chapter Review and NCLEX® Examination Preparation
Select the best answer for each question.
1. Number the following
... [Show More] drug forms in order of speed of dissolution and absorption, with
(1) being the fastest and (5) being the slowest: _____
a. Capsules__4___
b.Enteric-coated tablets __5___
c. Elixirs __3___
d. Powders ___2__
e. Orally disintegrating tablets __1____
2. When considering the various routes of drug elimination, the nurse is aware that
elimination occurs mainly by which routes?
a. Renal tubules and skin
b. Skin and lungs
c. Bowel and renal tubules
d. Lungs and gastrointestinal tract
3. The nurse is aware that excessive drug dosages, impaired metabolism, or inadequate
excretion may result in which drug effect?
a. Tolerance
b.Cumulative effect
c. Incompatibility
d.Antagonistic effect
4.Drug half-life is defined as the amount of time re- quired for 50% of a drug to:
a.be absorbed by the body.
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NURSING
b.reach a therapeutic level.
c.exert a response.
d.be removed by the body.
5.The nurse recognizes that drugs given by which route will be altered by the first-pass effect?
(Select all that apply.)
a. Oral
b. Sublingual
c. Subcutaneous
d. Intravenous
e. Rectal
6.If a drug binds with an enzyme and thereby prevents the enzyme from binding to its normal
target cell, it will produce which effect?
a. Receptor interaction
b. Enzyme affinity
c. Enzyme interaction
d. Nonspecific interaction
7.The nurse is reviewing a list of a patient’s medications, and notes that one of the drugs is
known to have a low therapeutic index. Which statement accurately explains this concept?
a. The difference between a therapeutic dose and toxic dose is large.
b. The difference between a therapeutic dose and toxic dose is small.
c. The dose needed to reach a therapeutic level is small.
d. The drug has only a slight chance of being effective. Continues..... [Show Less]