Cat and dog. Remember: Dust mite and cockroach allergens settle quickly. - ✔✔ Which types of allergens are most likely to be found in undisturbed
... [Show More] air in homes?
Grass (ie, northern grasses and Bermuda), ragweed, cat, dust mites, insect venom - ✔✔ Which allergen extracts are standardized?
1000-4000 BAU - ✔✔ What is the probable effective dose in biologic allergy units (BAU) for cat immunotherapy?
1:100 vol/vol - ✔✔ What does the blue allergen vial indicate (vol/vol)?
Th1-associated cytokines (IFN-y, IL-12) and Treg-associated (IL-10, TGF-beta) - ✔✔ What cytokines do you expect to increase after immunotherapy?
Timothy is cross-reactive to other northern grass (orchard, Kentucky bluegrass, perennial rye, sweet vernal, fescue, and red top) - ✔✔ What other grass is cross-reactive to Timothy grass?
4-6 months - ✔✔ How long does cat allergen remain in homes after cat removal?
Mold and cockroach - ✔✔ Which allergen extracts contain proteolytic enzymes which degrade pollen?
Vespid venoms (hornets and yellow jackets) - ✔✔ Which venom extracts can be mixed together?
5 and 20 μg of the major allergen per 0.5-mL maintenance dose - ✔✔ What is the effective maintenance dose for most inhalant allergens?
500-2000 BAU - ✔✔ What is the probable effective dose in biologic allergy units (BAU) for dust mite immunotherapy?
0.2% of injections lead to systemic reactions - ✔✔ What percent of allergen immunotherapy injections lead to systemic reactions?
1) Five-grass pollen tablet (Northern grass mix: Timothy, orchard, Kentucky blue, perennial rye, sweet vernal), 2) timothy only, 3) short ragweed, and 4) house dust mite - ✔✔ Which allergens/formulations are available with SLIT?
Selective inhibition of COX-2 - ✔✔ What type of COX inhibition is generally tolerated in patients with AERD?
Pro-inflammatory, eosinophil, and mast cell chemotaxis - ✔✔ What is the function of H4 receptor?
Neutrophils and eosinophils - ✔✔ LTB4 can lead to chemotaxis of which cell types?
Loratadine and first-generation antihistamines. For patients with hepatic failure: fexofenadine - ✔✔ Which antihistamines can be used with precaution in patients with renal failure?
PGE2 - ✔✔ In patients with AERD, COX inhibitor decreases the production of what prostaglandin product, leading to increased cys-LT production?
Formoterol; Salmeterol has a more lipophilic side chain, leading to slower onset - ✔✔ Between formoterol and salmeterol, which one has earlier onset of action?
Phosphodiesterase - ✔✔ What enzyme does theophylline inhibit, leading to increase in cAMP?
Macrolide antibiotics and ciprofloxacin - ✔✔ Which antibiotics result in increased serum levels of theophylline?
Ketoconazole, oral contraceptives, and macrolides (ie, troleandomycin) - ✔✔ Which medications decrease glucocorticoid metabolism?
PGE2 - ✔✔ In patients with AERD, COX inhibitor decreases the production of what prostaglandin product, leading to increased cys-LT production? [Show Less]